Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2 (Q34441960)

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English	Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2	scientific article

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scholarly article

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Europe PubMed Central

2 August 2017

Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2 (English)

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Europe PubMed Central

2 August 2017

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Hongtao Liu

1

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Europe PubMed Central

2 August 2017

Shujie Yu

2

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Europe PubMed Central

2 August 2017

Hua Zhang

3

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2 August 2017

Jian Xu

4

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2 August 2017

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3 October 2012

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2 August 2017

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Europe PubMed Central

2 August 2017

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2 August 2017

e46720

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Europe PubMed Central

2 August 2017

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Creative Commons Attribution 4.0 International

3 October 2012

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April 2022 Public Data File from Crossref

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3463541/fullTextXML

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VEGF signaling inside vascular endothelial cells and beyond

1 reference

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6 July 2018

The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells

1 reference

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6 July 2018

VEGFR2 translocates to the nucleus to regulate its own transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Structural variation in bacterial glyoxalase I enzymes: investigation of the metalloenzyme glyoxalase I from Clostridium acetobutylicum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Endothelial cell migration on fibronectin is regulated by syntaxin 6-mediated alpha5beta1 integrin recycling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Coupling in vitro and in vivo paradigm reveals a dose dependent inhibition of angiogenesis followed by initiation of autophagy by C6-ceramide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Glyoxalase in diabetes, obesity and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Regulation of vascular endothelial growth factor receptor 2 trafficking and angiogenesis by Golgi localized t-SNARE syntaxin 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Oxidative stress and diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

The emerging role of autophagy in the pathophysiology of diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Therapeutic targeting of mitochondrial superoxide in hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Trends in advanced glycation end products research in diabetes mellitus and its complications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Autophagy in vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

VEGF resistance as a molecular basis to explain the angiogenesis paradox in diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.

1 reference

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6 July 2018

Molecular insights and therapeutic targets for diabetic endothelial dysfunction

1 reference

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6 July 2018

Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension

1 reference

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6 July 2018

Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells

1 reference

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6 July 2018

AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice

1 reference

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6 July 2018

Autophagy: a sweet process in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Systems biology of vascular endothelial growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications

1 reference

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6 July 2018

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Receptor for advanced glycation end products (RAGE): a novel therapeutic target for diabetic vascular complication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Autophagy in the Pathogenesis of Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

1 reference

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6 July 2018

Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin alpha(6)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Nitric oxide and peroxynitrite in health and disease

1 reference

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6 July 2018

Vascular endothelial growth factor (VEGF)-Receptor2: its biological functions, major signaling pathway, and specific ligand VEGF-E.

1 reference

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6 July 2018

VEGF receptor signalling - in control of vascular function

1 reference

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6 July 2018

Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

1 reference

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6 July 2018

Endothelial cells and VEGF in vascular development

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6 July 2018

Angiogenesis in life, disease and medicine

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

6 July 2018

Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences

1 reference

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6 July 2018

The role of autophagy during the early neonatal starvation period

1 reference

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6 July 2018

Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation

1 reference

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6 July 2018

Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats

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6 July 2018

Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

2 references

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6 July 2018

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27 October 2018

Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice

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6 July 2018

Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.

1 reference

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6 July 2018

Abnormal angiogenesis in diabetes mellitus

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6 July 2018

VEGF receptor signal transduction

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6 July 2018

Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications

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6 July 2018

Vascular endothelial growth factor and diabetes: the agonist versus antagonist paradox

1 reference

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6 July 2018

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

1 reference

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6 July 2018

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts

1 reference

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6 July 2018

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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6 July 2018

Identification of a new endothelial cell growth factor receptor tyrosine kinase

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6 July 2018

VEGFR2 expression and TGF-β signaling in initial and recurrent high-grade human glioma.

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27 October 2018

The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

27 October 2018

MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus

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27 October 2018

Differential modulation of angiogenesis by advanced glycation end products.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

27 October 2018

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

1 reference

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27 October 2018

Impaired gastric ulcer healing in diabetic mice: role of methylglyoxal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

27 October 2018

Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells

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27 October 2018

More sugar, less blood vessels: another piece in the puzzle of increased cardiovascular risk in diabetes

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27 October 2018

Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus.

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27 October 2018

Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite.

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27 October 2018

Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease.

1 reference

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27 October 2018

Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility.

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27 October 2018

Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia

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27 October 2018

Diminished penile expression of vascular endothelial growth factor and its receptors at the insulin-resistant stage of a type II diabetic rat model: a possible cause for erectile dysfunction in diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463541

27 October 2018

Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice

1 reference

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27 October 2018

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress.

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27 October 2018

Glyoxalase I deficiency is associated with an unusual level of advanced glycation end products in a hemodialysis patient

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27 October 2018

VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment

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9 December 2018

Soluble CD146 displays angiogenic properties and promotes neovascularization in experimental hind-limb ischemia

1 reference

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12 December 2020

based on heuristic

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Inhibition of glyoxalase I by various clinically used anticancer drugs

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/23056421

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-induced inhibition of angiogenesis in the rat sponge granuloma is prevented by aminoguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23056421

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis, arteriogenesis, and diabetes: paradigm reassessed?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23056421

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/23056421

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy and angiogenesis inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23056421

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23056421

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0046720

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Europe PubMed Central

2 August 2017

2012PLoSO...746720L

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release_jqiiw2mjujehdjjwentx6gs32a

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https://api.fatcat.wiki/v0/release/jqiiw2mjujehdjjwentx6gs32a

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

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