Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage (Q34450499)

2 August 2017

1 reference

title

Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage (English)

1 reference

2 August 2017

0 references

1 reference

Jian Wang

1

1 reference

PubMed ID

16159103

2 August 2017

Stella E Tsirka

series ordinal

2

1 reference

2 August 2017

1 January 2005

1 reference

2 August 2017

1 reference

2 August 2017

3

1 reference

2 August 2017

1

1 reference

2 August 2017

77-85

1 reference

https://scigraph.springernature.com/pub.10.1385/ncc:3:1:077

2 August 2017

0 references

cites work

Clinical implications of the involvement of tPA in neuronal cell death

1 reference

12 December 2020

Suppression of cathepsins B and L causes a proliferation of lysosomes and the formation of meganeurites in hippocampus.

1 reference

12 December 2020

Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia

1 reference

12 December 2020

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

1 reference

12 December 2020

Hemorrhagic transformation following ischemic stroke: significance, causes, and relationship to therapy and treatment

1 reference

12 December 2020

Gelatinase B modulates selective opening of the blood-brain barrier during inflammation.

1 reference

12 December 2020

Plasminogen activators potentiate thrombin-induced brain injury.

1 reference

12 December 2020

Nuclear factor-kappaB and cell death after experimental intracerebral hemorrhage in rats

1 reference

12 December 2020

Protease inhibitors influence the direction of neurite outgrowth

1 reference

12 December 2020

Microglial secreted cathepsin B induces neuronal apoptosis.

1 reference

12 December 2020

Microglial invasion and activation in response to naturally occurring neuronal degeneration in the ganglion cell layer of the postnatal cat retina.

1 reference

12 December 2020

Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons.

1 reference

12 December 2020

Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition

1 reference

12 December 2020

Use of cocultured cell systems to elucidate chemokine-dependent neuronal/microglial interactions: control of microglial activation

1 reference

12 December 2020

Thrombin may contribute to the pathophysiology of central nervous system injury.

1 reference

12 December 2020

Thrombolytic stroke therapy: past, present, and future

1 reference

12 December 2020

The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations

1 reference

12 December 2020

Two novel cases of cerebral haemorrhages at the neonatal period associated with inherited factor VII deficiency, one of them revealing a new nonsense mutation (Ser52Stop).

1 reference

12 December 2020

Argatroban anticoagulation in patients with acute ischemic stroke (ARGIS-1): a randomized, placebo-controlled safety study

1 reference

12 December 2020

Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage.

1 reference

12 December 2020

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

1 reference

12 December 2020

Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II.

1 reference

12 December 2020

Thrombin-induced growth cone collapse: involvement of phospholipase A(2) and eicosanoid generation

1 reference

12 December 2020

Protective autoimmunity against the enemy within: fighting glutamate toxicity.

1 reference

12 December 2020

Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy.

1 reference

12 December 2020

Matrix metalloproteinases in brain injury

1 reference

12 December 2020

Matrix metalloproteinases: biologic activity and clinical implications

1 reference

12 December 2020

Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene

1 reference

12 December 2020

Dynamic changes of cathepsins B and L expression in the monkey hippocampus after transient ischemia.

1 reference

12 December 2020

Developmental plasticity of CNS microglia

1 reference

12 December 2020

A receptor for cathepsin G:alpha 1-antichymotrypsin complexes on mouse spinal cord astrocytes.

1 reference

12 December 2020

Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin

1 reference

12 December 2020

Regulation of protease-activated receptor 1 (PAR1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans

1 reference

12 December 2020

The role of the coagulation cascade in brain edema formation after intracerebral hemorrhage

1 reference

12 December 2020

Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.

1 reference

12 December 2020

Acute inflammatory reaction following experimental intracerebral hemorrhage in rat.

1 reference

12 December 2020

Prothrombin mRNA is expressed by cells of the nervous system.

1 reference

12 December 2020

Neurodegeneration of substantia nigra accompanied with macrophage/microglia infiltration after intrastriatal hemorrhage

1 reference

12 December 2020

Matrix metalloproteinases: they're not just for matrix anymore!

1 reference

12 December 2020

Intracerebral hemorrhage secondary to vascular lesions

1 reference

12 December 2020

Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion

1 reference

12 December 2020

Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes.

1 reference

12 December 2020

Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning.

1 reference

12 December 2020

The long-term effect of recombinant tissue-plasminogen-activator (rt-PA) on edema formation in a large-animal model of intracerebral hemorrhage

1 reference

12 December 2020

Matrix metalloproteinases in neuroinflammation

1 reference

12 December 2020

Antithrombin therapy for intracerebral hemorrhage

1 reference

12 December 2020

Central neurocytoma presenting with intratumoral hemorrhage

1 reference

12 December 2020

Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage

1 reference

12 December 2020

Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers

1 reference

12 December 2020

Thrombin-induced MCP-1 expression involves activation of the p22phox-containing NADPH oxidase in human vascular smooth muscle cells

1 reference

12 December 2020

Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system

1 reference

12 December 2020

Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

1 reference

12 December 2020

Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro.

1 reference

12 December 2020

Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases

1 reference

12 December 2020

Plasticity and stabilization of neuromuscular and CNS synapses: interactions between thrombin protease signaling pathways and tissue transglutaminase

1 reference

12 December 2020

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

1 reference

12 December 2020

Extracellular proteolysis in the adult murine brain

1 reference

12 December 2020

Microglial cathepsin B: an immunological examination of cellular and secreted species.

1 reference

12 December 2020

Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures.

1 reference

12 December 2020

The cellular reactions to experimental intracerebral hemorrhage

1 reference

12 December 2020

Cathepsin B-mediated activation of the proinflammatory caspase-11.

1 reference

12 December 2020

Mechanisms of edema formation after intracerebral hemorrhage: effects of extravasated red blood cells on blood flow and blood-brain barrier integrity.

1 reference

12 December 2020

Thrombin signalling and protease-activated receptors

1 reference

12 December 2020

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

12 December 2020

Molecular signatures of brain injury after intracerebral hemorrhage

1 reference

12 December 2020

Essential role of endogenous tissue plasminogen activator through matrix metalloproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischemia in mice

1 reference

12 December 2020

Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases

1 reference

12 December 2020

Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons.

1 reference

12 December 2020

The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate

1 reference

12 December 2020

Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration

1 reference

12 December 2020

Participation of protease-activated receptor-1 in thrombin-induced microglial activation

1 reference

12 December 2020

Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat.

1 reference

12 December 2020

New functions for the matrix metalloproteinases in cancer progression

1 reference

12 December 2020

Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study

1 reference

12 December 2020

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

1 reference

12 December 2020

Immunocompetent astrocytes and microglia display major differences in the processing of the invariant chain and in the expression of active cathepsin L and cathepsin S.

1 reference

12 December 2020

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

1 reference

12 December 2020

Apoptosis as a Form of Cell Death in Intracerebral Hemorrhage

1 reference

12 December 2020

Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation

1 reference

12 December 2020

Thrombolytic treatment of acute ischemic stroke

1 reference

12 December 2020

Astroglial and microglial activation in the wistar rat ventral tegmental area after a single striatal injection of 6-hydroxydopamine

1 reference

12 December 2020

Plasminogen expression in the neonatal and adult mouse brain.

1 reference

12 December 2020

Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent

1 reference

12 December 2020

Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons

1 reference

12 December 2020

The role of endogenous versus exogenous tPA on edema formation in murine ICH.

1 reference

12 December 2020

Thrombin Induces Proteinase-activated Receptor-1 Gene Expression in Endothelial Cells via Activation of Gi-linked Ras/Mitogen-activated Protein Kinase Pathway

1 reference

12 December 2020

Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA.

1 reference

12 December 2020

Identification of Cathepsin B as a Mediator of Neuronal Death Induced by Aβ-activated Microglial Cells Using a Functional Genomics Approach

1 reference

12 December 2020

Cathepsin B and middle cerebral artery occlusion in the rat.

1 reference

12 December 2020

Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior

1 reference

12 December 2020

Intraarterial recombinant tissue plasminogen activator for ischemic stroke: an accelerating dosing regimen

1 reference

12 December 2020

Expression of the thrombin receptor mRNA in rat brain.

1 reference

12 December 2020

Triggers and mediators of hemorrhagic transformation in cerebral ischemia

1 reference

12 December 2020

Pathogenic A beta induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells.

1 reference

12 December 2020

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity

1 reference

12 December 2020

Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B

1 reference

12 December 2020

Microglial apoptosis induced by chromogranin A is mediated by mitochondrial depolarisation and the permeability transition but not by cytochrome c release

1 reference

12 December 2020

Evidence for apoptosis after intercerebral hemorrhage in rat striatum

1 reference

12 December 2020

Evidence that inhibition of cathepsin-B contributes to the neuroprotective properties of caspase inhibitor Tyr-Val-Ala-Asp-chloromethyl ketone.

1 reference

12 December 2020

Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke.

1 reference

12 December 2020

Microglia: a sensor for pathological events in the CNS

1 reference

12 December 2020

Serine proteases and brain damage - is there a link?

1 reference

12 December 2020

Matrix metalloproteinases and atherosclerosis

1 reference

12 December 2020

Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors

1 reference

12 December 2020

Metalloproteinases in biology and pathology of the nervous system.

1 reference

12 December 2020

Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia

1 reference

12 December 2020

Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway.

1 reference

12 December 2020

Metalloproteinase inhibitors: biological actions and therapeutic opportunities.

1 reference

12 December 2020

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

1 reference

12 December 2020

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

1 reference

12 December 2020

Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood

1 reference

12 December 2020

Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage.

1 reference

12 December 2020

Novel therapies for intracerebral hemorrhage

1 reference

12 December 2020

Expression of rat cathepsin S in phagocytic cells

1 reference

12 December 2020

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

1 reference

12 December 2020

Permissive proteolytic activity for visual cortical plasticity

1 reference

12 December 2020

Plasma beta-amyloid peptide, transforming growth factor-beta 1, and risk for cerebral amyloid angiopathy

1 reference

12 December 2020

Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

1 reference

12 December 2020

Role of blood clot formation on early edema development after experimental intracerebral hemorrhage.

1 reference

12 December 2020

Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain.

1 reference

12 December 2020

Identifiers

DOI

10.1385/NCC:3:1:077

1 reference

PubMed ID

16159103

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

16159103