Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo (Q34461960)

24284042

2 August 2017

title

Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo (English)

1 reference

2 August 2017

1 reference

5

1 reference

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9 June 2020

Joon Won Park

11

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9 June 2020

Michael J Rowan

14

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9 June 2020

Jung Hoon Jung

4

1 reference

ORCID Public Data File 2021

author name string

Kyongman An

1

1 reference

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9 June 2020

Igor Klyubin

2

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9 June 2020

Youngkyu Kim

3

1 reference

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9 June 2020

Sean T O'Dowd

6

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9 June 2020

Timothy Lynch

7

1 reference

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9 June 2020

Daniel Kanmert

8

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9 June 2020

Cynthia A Lemere

9

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9 June 2020

Gina M Finan

10

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9 June 2020

Tae-Wan Kim

12

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9 June 2020

Dominic M Walsh

13

1 reference

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9 June 2020

Joung-Hun Kim

15

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9 June 2020

publication date

13 November 2013

1 reference

2 August 2017

1 reference

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9 June 2020

volume

6

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9 June 2020

page(s)

47

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Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change

9 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Alzheimer's disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Resolving controversies on the path to Alzheimer's therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

The prion protein as a receptor for amyloid-beta.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Memory impairment in transgenic Alzheimer mice requires cellular prion protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Packaging of prions into exosomes is associated with a novel pathway of PrP processing.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Alzheimer's disease is a synaptic failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Exosomes: composition, biogenesis and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor

6 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

6 July 2018

https://pubmed.ncbi.nlm.nih.gov/24284042

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Clearing the brain's amyloid cobwebs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Formation of toxic Abeta(1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: polymorphisms in Abeta(1-40) fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Neuroprotective Effect of Ganglioside GM1 on the Cytotoxic Action of Hydrogen Peroxide and Amyloid β-peptide in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Self-assembly of Abeta(1-42) into globular neurotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

The cellular prion protein and its role in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Prions prevent neuronal cell-line death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Differential effects of Phe19 and Phe20 on fibril formation by amyloidogenic peptide A beta 16-22 (Ac-KLVFFAE-NH2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Exosomes: the Trojan horses of neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-47

Beta-amyloid monomers are neuroprotective.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222117

Sampling and analysis of cerebrospinal fluid for chronic studies in awake rats

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24284042

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24284042

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1756-6606-6-47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24284042%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24284042%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

24284042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24284042%20AND%20SRC:MED&resulttype=core&format=json