HIV-1 and interferons: who's interfering with whom? (Q34473801)

2 August 2017

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title

HIV-1 and interferons: who's interfering with whom? (English)

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2 August 2017

3

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2 August 2017

Tomas Doyle

1

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2 August 2017

Caroline Goujon

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

27 April 2015

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Nature Reviews Microbiology

2 August 2017

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2 August 2017

13

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2 August 2017

7

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2 August 2017

403-413

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https://scigraph.springernature.com/pub.10.1038/nrmicro3449

2 August 2017

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cites work

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Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals

31 March 2020

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Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T c

31 March 2020

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Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics

31 March 2020

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Interferon, a growing cytokine family: 50 years of interferon research

31 March 2020

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A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferon signalling network in innate defence

31 March 2020

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Type I interferons in infectious disease

31 March 2020

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Interferon-inducible effector mechanisms in cell-autonomous immunity

31 March 2020

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Interferon-stimulated genes: roles in viral pathogenesis

31 March 2020

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A diverse range of gene products are effectors of the type I interferon antiviral response

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Systematic identification of type I and type II interferon-induced antiviral factors

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Cytosolic sensing of viruses

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

HIV-1 evades innate immune recognition through specific cofactor recruitment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

IFI16 is an innate immune sensor for intracellular DNA

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3449

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Innate sensing of HIV-infected cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Intracellular toll-like receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Plasmacytoid dendritic cell dynamics tune interferon-alfa production in SIV-infected cynomolgus macaques

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Hiding in plain sight: how HIV evades innate immune responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Retroviral retention activates a Syk-dependent HemITAM in human tetherin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Human immunodeficiency virus, restriction factors, and interferon

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Intrinsic antiviral immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

HIV Restriction Factors and Mechanisms of Evasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

HIV Interplay with SAMHD1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Origins of HIV and the AIDS pandemic

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Recombinant human interferon alfa-A suppresses HTLV-III replication in vitro.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Mechanisms for the inhibition of HIV replication by interferons-alpha, -beta, and -gamma in primary human macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferon-alpha mediates restriction of human immunodeficiency virus type-1 replication in primary human macrophages at an early stage of replication

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The interferon-inducible MxB protein inhibits HIV-1 infection.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

MX2 is an interferon-induced inhibitor of HIV-1 infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Structural insight into HIV-1 restriction by MxB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

The IFITM proteins inhibit HIV-1 infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferon type I responses in primary and secondary infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Phenotypic properties of transmitted founder HIV-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Relative resistance of HIV-1 founder viruses to control by interferon-alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferon-alpha in patients with asymptomatic human immunodeficiency virus (HIV) infection. A randomized, placebo-controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Differential antiviral effect of PEG-interferon-alpha-2b on HIV and HCV in the treatment of HIV/HCV co-infected patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Host gene expression changes correlating with anti-HIV-1 effects in human subjects after treatment with peginterferon Alfa-2a

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferon signaling and treatment outcome in chronic hepatitis C

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Hepatitis C therapy with interferon-α and ribavirin reduces CD4 T-cell-associated HIV-1 DNA in HIV-1/hepatitis C virus-coinfected patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Immunologic strategies for HIV-1 remission and eradication

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Emerging concepts in the immunopathogenesis of AIDS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Virus-induced transient immune suppression and the inhibition of T cell proliferation by type I interferon

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Regulating the diverse outcomes of interferon's interference

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Positional cloning of the mouse retrovirus restriction gene Fv1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

NK cells and interferons.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Type I IFN contributes to NK cell homeostasis, activation, and antitumor function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Analysis of apoptosis of memory T cells and dendritic cells during the early stages of viral infection or exposure to toll-like receptor agonists

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Direct effects of type I interferons on cells of the immune system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3449

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

31 March 2020

1 reference

12 December 2020

Alpha interferon inhibits early stages of the human immunodeficiency virus type 1 replication cycle

1 reference

12 December 2020

Functional classification of interferon-stimulated genes identified using microarrays

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12 December 2020

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

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12 December 2020

The antiviral activities of tetherin

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12 December 2020

Identifiers

DOI

10.1038/NRMICRO3449

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Dimensions Publication ID

2 August 2017

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