Transcription Regulation by Class III Histone Deacetylases (HDACs)-Sirtuins. (Q34497747)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

review article

1 reference

title

Transcription Regulation by Class III Histone Deacetylases (HDACs)-Sirtuins (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1

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31 January 2020

author name string

Douglas V Faller

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

publication date

23 April 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

Translational Oncogenomics

31 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

3

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31 January 2020

page(s)

53-65

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation

31 January 2020

cites work

1 reference

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Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis

7 July 2018

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Regulation of protein turnover by acetyltransferases and deacetylases.

7 July 2018

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SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation

7 July 2018

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Dynamic FoxO transcription factors

7 July 2018

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Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

7 July 2018

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SIRT1 is significantly elevated in mouse and human prostate cancer.

7 July 2018

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Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

7 July 2018

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SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

7 July 2018

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Cytoplasm-localized SIRT1 enhances apoptosis

7 July 2018

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Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor

7 July 2018

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SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

7 July 2018

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Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells

7 July 2018

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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

7 July 2018

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Phosphorylation of HuR by Chk2 regulates SIRT1 expression

7 July 2018

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An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity

7 July 2018

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EZH2 promotes proliferation and invasiveness of prostate cancer cells

7 July 2018

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Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

7 July 2018

1 reference

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

7 July 2018

1 reference

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The role of NAD+ dependent histone deacetylases (sirtuins) in ageing

7 July 2018

1 reference

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SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

7 July 2018

1 reference

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SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Hormonal control of androgen receptor function through SIRT1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

7 July 2018

1 reference

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EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

7 July 2018

1 reference

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Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

7 July 2018

1 reference

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Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

7 July 2018

1 reference

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FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

7 July 2018

1 reference

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Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

7 July 2018

1 reference

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Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins.

7 July 2018

1 reference

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

7 July 2018

1 reference

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SIRT1 regulates HIV transcription via Tat deacetylation

7 July 2018

1 reference

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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

The Sir2 family of protein deacetylases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

7 July 2018

1 reference

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Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)

7 July 2018

1 reference

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The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

7 July 2018

1 reference

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Mammalian SIRT1 represses forkhead transcription factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Class II histone deacetylases: versatile regulators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Histone deacetylases (HDACs): characterization of the classical HDAC family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Control of Smad7 stability by competition between acetylation and ubiquitination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

The polycomb group protein EZH2 is involved in progression of prostate cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Negative control of p53 by Sir2alpha promotes cell survival under stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2alpha.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022360

Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism

27 October 2018

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12 December 2020

Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

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12 December 2020

[H2A.Z: a histone variant that decorates gene promoters]

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12 December 2020

HuR-SIRT: the hairy world of posttranscriptional control

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12 December 2020

Identifiers

DOI

10.4137/TOG.S483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21566744%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference