PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation (Q34514602)

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English	PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation (English)

1 reference

Europe PubMed Central

2 August 2017

author name string

Omar M Rahal

1

1 reference

Europe PubMed Central

2 August 2017

Rosalia C M Simmen

2

1 reference

Europe PubMed Central

2 August 2017

language of work or name

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publication date

16 June 2010

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

31

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Europe PubMed Central

2 August 2017

8

1 reference

Europe PubMed Central

2 August 2017

1491-1500

1 reference

Europe PubMed Central

2 August 2017

GPR30/GPER1: searching for a role in estrogen physiology

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7 July 2018

Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Early soy exposure via maternal diet regulates rat mammary epithelial differentiation by paracrine signaling from stromal adipocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Id-1 activates Akt-mediated Wnt signaling and p27(Kip1) phosphorylation through PTEN inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Soy isoflavone genistein upregulates epithelial adhesion molecule E-cadherin expression and attenuates beta-catenin signaling in mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN: a new guardian of the genome.

1 reference

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7 July 2018

The role of early life genistein exposures in modifying breast cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations

1 reference

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7 July 2018

Cancer statistics, 2008

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7 July 2018

The nuclear affairs of PTEN.

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7 July 2018

Epidemiology of soy exposures and breast cancer risk

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Modelling breast cancer: one size does not fit all.

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7 July 2018

Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Timing of dietary estrogenic exposures and breast cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Genistein protects human mammary epithelial cells from benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S-transferase system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN deletion leads to up-regulation of a secreted growth factor pleiotrophin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Progesterone receptor transactivation of the secretory leukocyte protease inhibitor gene in Ishikawa endometrial epithelial cells involves recruitment of Krüppel-like factor 9/basic transcription element binding protein-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Class reunion: PTEN joins the nuclear crew.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Regulation of PTEN transcription by p53

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Protection against breast cancer with genistein: a component of soy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN and inherited hamartoma-cancer syndromes.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

7 July 2018

The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today

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7 July 2018

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

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7 July 2018

Adolescent and adult soy intake and risk of breast cancer in Asian-Americans

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ123

21 January 2018

Inhibition of NMU-induced mammary tumorigenesis by dietary soy.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ123

21 January 2018

Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ123

21 January 2018

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ123

21 January 2018

Uterine phenotype of young adult rats exposed to dietary soy or genistein during development

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ123

21 January 2018

Phytoestrogen concentrations in serum from Japanese men and women over forty years of age.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

27 October 2018

Diets containing whey proteins or soy protein isolate protect against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in female rats.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025717

27 October 2018

Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas.

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27 October 2018

PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent Manner

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21 January 2018

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

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21 January 2018

AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma phytoestrogens and subsequent breast cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/20554748

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women

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https://pubmed.ncbi.nlm.nih.gov/20554748

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure of infants to phyto-oestrogens from soy-based infant formula

1 reference

https://pubmed.ncbi.nlm.nih.gov/20554748

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CARCIN/BGQ123

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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