Telomeres and telomerase: a dual role in hepatocarcinogenesis (Q34550878)

3 August 2017

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title

Telomeres and telomerase: a dual role in hepatocarcinogenesis (English)

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3 August 2017

2

Michael P Manns

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3 August 2017

Ande Satyanarayana

1

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PubMed ID

15368430

3 August 2017

K Lenhard Rudolph

series ordinal

3

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PubMed ID

15368430

3 August 2017

language of work or name

English

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publication date

1 August 2004

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3 August 2017

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3 August 2017

40

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3 August 2017

276-283

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3 August 2017

2

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Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

3 August 2017

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Telomerase activity in Hodgkin's disease.

21 January 2018

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Structure and function of telomeres

21 January 2018

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7 January 2021

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

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7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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7 January 2021

The end replication problem: more than one solution.

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7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

The two-stage mechanism controlling cellular senescence and immortalization

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7 January 2021

Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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7 January 2021

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

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7 January 2021

Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery

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7 January 2021

Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells

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7 January 2021

Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis

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7 January 2021

Telomerase activity in hepatocellular carcinoma and adjacent liver tissues

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7 January 2021

Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma

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7 January 2021

Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease

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7 January 2021

Cellular distribution of telomerase reverse transcriptase in human hepatocellular carcinoma

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7 January 2021

Telomere length variation and maintenance in hepatocarcinogenesis.

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7 January 2021

In situdetection of telomerase enzymatic activity in human hepatocellular carcinogenesis

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7 January 2021

Telomerase activity in hepatocellular carcinoma as a predictor of postoperative recurrence

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7 January 2021

Growth inhibition of BEL-7404 human hepatoma cells by expression of mutant telomerase reverse transcriptase.

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7 January 2021

Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers

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7 January 2021

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.

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7 January 2021

Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma

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7 January 2021

Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.

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7 January 2021

Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness.

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7 January 2021

Telomerase and breast cancer

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7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

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7 January 2021

Telomere shortening in gastric carcinoma with aging despite telomerase activation.

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7 January 2021

Telomerase activity in benign and malignant adrenal tumors

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7 January 2021

Consistent decrease in telomere length in parathyroid tumors but alteration in telomerase activity limited to malignancies: preliminary report

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7 January 2021

Telomerase activity and the expression of telomerase components in pituitary adenoma with malignant transformation

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7 January 2021

Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications

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7 January 2021

Telomerase activity and telomere lengths: alterations in renal cell carcinomas

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7 January 2021

Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors

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7 January 2021

Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.

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7 January 2021

Telomerase activity is frequently found in metaplastic and malignant human nasopharyngeal tissues

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7 January 2021

Telomerase activity in oral and maxillofacial tumors

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7 January 2021

Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage

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7 January 2021

Shortened telomere length is demonstrated in T-cell subsets together with a pronounced increased telomerase activity in CD4 positive T cells from blood of patients with mycosis fungoides and parapsoriasis

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7 January 2021

Telomerase activity in plasma cell dyscrasias

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7 January 2021

Telomerase activity in small-cell and non-small-cell lung cancers

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7 January 2021

Expression of telomerase reverse transcriptase (TERT) in malignant mesotheliomas.

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7 January 2021

Telomerase in brain tumors.

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7 January 2021

Expression of telomerase RNA component correlates with the MIB-1 proliferation index in ependymomas

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7 January 2021

Telomerase activity in melanoma and non-melanoma skin cancer

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7 January 2021

Quantitative in situ evaluation of telomeres in fluorescence in situ hybridization-processed sections of cutaneous melanocytic lesions and correlation with telomerase activity.

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7 January 2021

Telomerase activity of Merkel cell carcinomas and Merkel cell carcinoma-derived cell cultures

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7 January 2021

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

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7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

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7 January 2021

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

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7 January 2021

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

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7 January 2021

Genetic instabilities in human cancers

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7 January 2021

Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse

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7 January 2021

Comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) in the diagnosis of hepatocellular carcinoma

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7 January 2021

DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.

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7 January 2021

Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesis

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7 January 2021

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation

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7 January 2021

INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas.

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7 January 2021

ATM: a mediator of multiple responses to genotoxic stress

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7 January 2021

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

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7 January 2021

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

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7 January 2021

Identifiers

DOI

10.1002/HEP.20308

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3 August 2017

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PubMed ID

15368430