The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism (Q34557750)

3 August 2017

title

The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism (English)

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3 August 2017

Peijun Liu

1

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3 August 2017

Laura R Barkley

2

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3 August 2017

Tovah Day

3

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3 August 2017

Xiaohui Bi

4

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3 August 2017

Damien M Slater

5

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3 August 2017

Mark G Alexandrow

6

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3 August 2017

Heinz-Peter Nasheuer

7

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3 August 2017

Cyrus Vaziri

8

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3 August 2017

language of work or name

English

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publication date

15 August 2006

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Journal of Biological Chemistry

3 August 2017

published in

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3 August 2017

volume

281

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3 August 2017

issue

41

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3 August 2017

page(s)

30631-30644

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The DNA damage response: putting checkpoints in perspective

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Radiation down-regulates replication origin activity throughout the S phase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

DNA adducts of chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Effect of benzo[a]pyrene-diol-epoxide-I on growth of nascent DNA in synchronized human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Checking on DNA damage in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Cdc7 kinase complex: a key regulator in the initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The Cdc7 protein kinase is required for origin firing during S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

A p53-dependent checkpoint pathway prevents rereplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

DNA damage responses protect xeroderma pigmentosum variant from UVC-induced clastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Regulation of eukaryotic DNA replication at the initiation step

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: precise choreography of condensation/decondensation and nuclear positioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The mammalian beta globin origin of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Active Localization of the Retinoblastoma Protein in Chromatin and Its Response to S Phase DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Rapid destruction of human Cdc25A in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

DNA replication and progression through S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Human CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Cell-cycle checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Toward maintaining the genome: DNA damage and replication checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Cut5 Is Required for the Binding of Atr and DNA Polymerase α to Genotoxin-damaged Chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Identification and functional analysis of TopBP1 and its homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

ATM-dependent dissociation of B55 regulatory subunit from nuclear PP2A in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602982200

21 January 2018

Identifiers

DOI

10.1074/JBC.M602982200

1 reference

3 August 2017

1 reference