Targeting of toxic compounds to the trypanosome's interior (Q34585708)

3 August 2017

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title

Targeting of toxic compounds to the trypanosome's interior (English)

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3 August 2017

1

Michael P Barrett

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Ian H. Gilbert

object named as

Ian H Gilbert

series ordinal

2

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author name string

Michael P Barrett

series ordinal

1

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3 August 2017

1 January 2006

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3 August 2017

Advances in Parasitology

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3 August 2017

63

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3 August 2017

125-183

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Metabolism and action of amino acid analog anti-cancer agents

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Novel motifs in amino acid permease genes from Leishmania

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The role of Trypanosoma brucei MRPA in melarsoprol susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Options for vector control against trypanosomiasis in Africa.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

In vitro metabolism of an orally active O-methyl amidoxime prodrug for the treatment of CNS trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Successful treatment of experimental murine Trypanosoma brucei infection with topical melarsoprol gel.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Chemical and enzymatic synthesis of fructose analogues as probes for import studies by the hexose transporter in parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Interaction of substituted hexose analogues with the Trypanosoma brucei hexose transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Effects of antagonists of polyamine metabolism on African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Polyamine metabolism: a potential therapeutic target in trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

5'-Alkyl-substituted analogs of 5'-methylthioadenosine as trypanocides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

What Controls Glycolysis in Bloodstream FormTrypanosoma brucei?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Contribution of glucose transport to the control of the glycolytic flux in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Alteration of pyruvate metabolism in African trypanosomes during differentiation from bloodstream into insect forms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Problems for the chemotherapy of human African trypanosomiasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Veterinary link to drug resistance in human African trypanosomiasis?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Anti-sleeping Sickness Drugs and Cancer Chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Functional expression and characterization of the Trypanosoma brucei procyclic glucose transporter, THT2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosome glucose transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Structure and function of facilitative sugar transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of the nitroimidazole drug megazol by African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

1 reference

7 January 2021

An M(r) 145,000 low-density lipoprotein (LDL)-binding protein is conserved throughout the Kinetoplastida order

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Complementation of a glucose transporter mutant of Schizosaccharomyces pombe by a novel Trypanosoma brucei gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Triazinyl derivatives that are potent inhibitors of glucose transport in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Aquaporins from pathogenic protozoan parasites: structure, function and potential for chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Biochemical changes associated with alpha-difluoromethylornithine uptake and resistance in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Is metronidazole carcinogenic?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Polyamine and pentamidine metabolism in African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Characterisation of pentamidine-resistant Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Aromatic amino acid transamination and methionine recycling in trypanosomatids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The Genome of the African Trypanosome Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Necessity of antibody response in the treatment of African trypanosomiasis with alpha-difluoromethylornithine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The role of transferrin-receptor variation in the host range of Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Post genomic analysis of permeases from the amino acid/auxin family in protozoan parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A potential hexose transporter gene expressed predominantly in the bloodstream form of Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The phenomenon of treatment failures in Human African Trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Eflornithine for the treatment of human African trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pharmacokinetic properties of the trypanocidal drug melarsoprol

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of the antitrypanosomal drug 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine (MDL 73811) by the purine transport system of Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Nucleoside transporters of parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Novel inhibitors of Leishmanial dihydrofolate reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The adaptative mechanisms of Trypanosoma brucei for sterol homeostasis in its different life-cycle environments

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Antiprotozoal activities of phospholipid analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pteridine salvage throughout the Leishmania infectious cycle: implications for antifolate chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pentamidine Transport and Sensitivity inbrucei-Group Trypanosomes*

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pentamidine transport in Trypanosoma brucei—Kinetics and specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The serum resistance-associated (SRA) gene of Trypanosoma brucei rhodesiense encodes a variant surface glycoprotein-like protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Transporters in African trypanosomes: role in drug action and resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Characterization of a Nucleoside/Proton Symporter in ProcyclicTrypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake and mode of action of drugs used against sleeping sickness.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The efficacy of pentamidine in the treatment of early-late stage Trypanosoma brucei gambiense trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Paul Ehrlich: magister mundi.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Prospects for antiparasitic drugs. The case of Trypanosoma brucei, the causative agent of African sleeping sickness

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Specificity and kinetics of hexose transport in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Drug resistance in Sudanese Trypanosoma evansi

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Megazol combined with suramin: a chemotherapy regimen which reversed the CNS pathology in a model of human African trypanosomiasis in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Activity of megazol, a trypanocidal nitroimidazole, is associated with DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Kinetics of endocytosis and recycling of the GPI-anchored variant surface glycoprotein in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of alpha-difluoromethylornithine by mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Chemotherapy of human African trypanosomiasis: current and future prospects

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosoma brucei: Suramin and other trypanocidal compounds' effects on sn-glycerol-3-phosphate oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of the trypanocidal drug suramin by bloodstream forms of Trypanosoma brucei and its effect on respiration and growth rate in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

New approach to screening drugs for activity against African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanothione is the primary target for arsenical drugs against African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Reanalyzing the 1900-1920 sleeping sickness epidemic in Uganda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Susceptibility and natural resistance of Trypanosoma cruzi strains to drugs used clinically in Chagas disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Transport of D-fructose and its analogues by Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Molecular pharmacology of adenosine transport in Trypanosoma brucei: P1/P2 revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The physiological significance of transferrin receptor variations in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Slow-release melarsoprol microparticles.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A new VSG expression site-associated gene (ESAG) in the promoter region of Trypanosoma brucei encodes a protein with 10 potential transmembrane domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Evidence for a Trypanosoma brucei lipoprotein scavenger receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Increased urinary excretion of aromatic amino acid catabolites by Microtus montanus chronically infected with Trypanosoma brucei gambiense

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosoma gambiense: membrane transport of amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Drug uptake via nutrient transporters in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Transport of methionine in Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Identification and characterization of a polyamine permease from the protozoan parasite Leishmania major

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The Distribution of 4: 4′-Diamidino Stilbene in Trypanosomes and Mice as Shown by Fluorescence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

"Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Comparative effects of diverse mammalian sera on the uptake and protein incorporation of 14C-labelled amino acids by blood stream forms of T. brucei and T. rhodesiense in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of purine bases and nucleosides in African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Topical melarsoprol for trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

New drugs for the treatment of human African trypanosomiasis: research and development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pharmacology of existing drugs for animal trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Glycerol kinase of Trypanosoma brucei. Cloning, molecular characterization and mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Molecular genetics of nucleoside transporters in Leishmania and African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Nucleoside and nucleobase transporters in parasitic protozoa.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Leishmaniasis: efflux pumps and chemoresistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

ABC proteins of Leishmania

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Risk factors for treatment failure after melarsoprol for Trypanosoma brucei gambiense trypanosomiasis in Uganda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Treatment of human African trypanosomiasis--present situation and needs for research and development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Regulation of a high-affinity diamine transport system in Trypanosoma cruzi epimastigotes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Active transport of L-proline in the protozoan parasite Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosoma brucei brucei: characterization of an ODC null bloodstream form mutant and the action of alpha-difluoromethylornithine.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Arsenic trioxide uptake by human and rat aquaglyceroporins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Drug transport and drug resistance in African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Antigenic variation in African trypanosomes: monitoring progress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The acquisition of lipids by African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

An approach to the development of new drugs for African trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Re-emergence of epidemic sleeping sickness in southern Sudan

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Molecular characterization of susceptible and naturally resistant strains of Trypanosoma cruzi to benznidazole and nifurtimox.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Factors affecting the level and localization of the transferrin receptor in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Effects of aphidicolin and hydroxyurea on the cell cycle and differentiation of Trypanosoma brucei bloodstream forms.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Differences in cloning and sub-cloning success rates in four stocks of Trypanosoma evansi and variation in suramin resistance of the clones

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Slender and stumpy bloodstream forms of Trypanosoma brucei display a differential response to extracellular acidic and proteolytic stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Compartmentation of carbohydrate metabolism in trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei : The glycosome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The potential use of inhibitors of glycerol-3-phosphate oxidase for chemotherapy of African trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Particle-Bound Enzymes in the Bloodstream Form of Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pterin transport and metabolism in Leishmania and related trypanosomatid parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Active-Site-Directed Inhibition of the Plasma-Membrane Carrier Transporting Short-Chain, Neutral Amino Acids into Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

An open clinical trial of nifurtimox for arseno-resistant Trypanosoma brucei gambiense sleeping sickness in central Zaire

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pharmacology of diminazene: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Sinefungin shares AdoMet-uptake system to enter Leishmania donovani promastigotes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A Trypanosoma brucei mutant resistant to alpha-difluoromethylornithine.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A new type of high affinity folic acid transporter in the protozoan parasite Leishmania and deletion of its gene in methotrexate-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Growth phase regulation of the main folate transporter of Leishmania infantum and its role in methotrexate resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Alteration to one of three adenosine transporters is associated with resistance to cymelarsan in Trypanosoma evansi

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Metabolism of phospholipids and lysophospholipids by Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Transferrin is a growth factor for the bloodstream form ofTrypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A transferrin-binding protein of Trypanosoma brucei is encoded by one of the genes in the variant surface glycoprotein gene expression site.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Silencing of the thioredoxin gene in Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Natural and induced dyskinetoplastic trypanosomatids: how to live without mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Specificity of glucose transport in Trypanosoma brucei. Effective inhibition by phloretin and cytochalasin B

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Functional reconstitution of the Trypanosoma brucei plasma-membrane D-glucose transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

In vitro trypanocidal activity of dibutyltin dichloride and its fatty acid derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Uptake of NO-releasing drugs by the P2 nucleoside transporter in trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Synthesis and uptake of nitric oxide-releasing drugs by the P2 nucleoside transporter in Trypanosoma equiperdum

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The situation of sleeping sickness in Angola: a calamity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Cloning, heterologous expression and kinetic analysis of glycerol kinase (TbGLK1) from Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Transferrin-binding protein complex is the receptor for transferrin uptake in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Trypanocidal activity of melamine-based nitroheterocycles

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Synthesis and evaluation of the in vivo trypanocidal activity of water soluble organotin compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Kinetoplastid glucose transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Maintenance of internal pH and an electrochemical gradient in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Comparative studies of nifurtimox uptake and metabolism by drug-resistant and susceptible strains of Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Synthesis and antitrypanosomal evaluation of some thiazole-containing amino acids and peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Apolipoprotein L-I is the trypanosome lytic factor of human serum

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Effects of various metabolic conditions and of the trivalent arsenical melarsen oxide on the intracellular levels of fructose 2,6-bisphosphate and of glycolytic intermediates in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The uptake of the trypanocidal drug suramin in combination with low-density lipoproteins by Trypanosoma brucei and its possible mode of action

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Glycolysis as a target for the design of new anti-trypanosome drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Enzymatic reduction studies of nitroheterocycles

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Studies on the active site of the N1 amino acid transport carrier of T. brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Changes in the kinetic behaviour of threonine transport into Trypanosoma brucei elicited by variation in hydrogen ion concentration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Fatty acid uptake by bloodstream forms of Trypanosoma brucei and other species of the kinetoplastida

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Selective transport of a new class of purine antimetabolites by the protozoan parasite Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Sugar transporters from bacteria, parasites and mammals: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pyruvate transport across the plasma membrane of the bloodstream form of Trypanosoma brucei is mediated by a facilitated diffusion carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The inhibition of pyruvate transport across the plasma membrane of the bloodstream form of Trypanosoma brucei and its metabolic implications.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Characterization of glycerol uptake in bloodstream and procyclic forms of Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A VSG expression site-associated gene confers resistance to human serum in Trypanosoma rhodesiense

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Effect of DL-alpha-difluoromethylornithine on methionine cycle intermediates in Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Transport of nutrients and ions across membranes of trypanosomatid parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

The treatment of human African trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Kinetoplast DNA in trypanosomid flagellates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

Pharmacological approaches to antitrypanosomal chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-308X%2806%2963002-9

7 January 2021

10.1016/S0065-308X(06)63002-9

Identifiers

DOI

1 reference

release_qvsilttzlbdg3jdl5rmujz4a4m

3 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qvsilttzlbdg3jdl5rmujz4a4m

24 November 2022

mapped directly with Wikidata item

PubMed ID

17134653

1 reference

PubMed ID

17134653