Presenilin-based genetic screens in Drosophila melanogaster identify novel notch pathway modifiers (Q34588474)

3 August 2017

title

Presenilin-based genetic screens in Drosophila melanogaster identify novel notch pathway modifiers (English)

1 reference

3 August 2017

main subject

Drosophila melanogaster

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Annette L Parks

2

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author name string

Matt B Mahoney

1

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3 August 2017

David A Ruddy

3

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3 August 2017

Stanley Y K Tiong

4

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3 August 2017

Hanife Esengil

5

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3 August 2017

Alexander C Phan

6

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3 August 2017

Panos Philandrinos

7

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3 August 2017

Christopher G Winter

8

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3 August 2017

Runa Chatterjee

9

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3 August 2017

Kari Huppert

10

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3 August 2017

William W Fisher

11

1 reference

3 August 2017

Lynn L'Archeveque

12

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3 August 2017

Felipa A Mapa

13

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3 August 2017

Wendy Woo

14

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3 August 2017

Michael C Ellis

15

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3 August 2017

Daniel Curtis

16

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3 August 2017

language of work or name

English

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publication date

16 January 2006

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3 August 2017

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3 August 2017

volume

172

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3 August 2017

issue

4

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3 August 2017

page(s)

2309-2324

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Presenilin function and gamma-secretase activity

3 August 2017

cites work

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Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

7 July 2018

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Multiple niches for Notch in cancer: context is everything

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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gamma-tubulin plays an essential role in the coordination of mitotic events

7 July 2018

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7 July 2018

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The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains

7 July 2018

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Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein.

7 July 2018

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7 July 2018

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

7 July 2018

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Notch signaling and inherited disease syndromes

7 July 2018

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An overview of the Notch signalling pathway

7 July 2018

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Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

7 July 2018

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The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila

7 July 2018

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Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferase

7 July 2018

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General outlines of the molecular genetics of the Notch signalling pathway in Drosophila melanogaster: a review

7 July 2018

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Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells

7 July 2018

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aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

7 July 2018

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The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane.

7 July 2018

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Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation

7 July 2018

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Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz

7 July 2018

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APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

7 July 2018

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New frontiers in Alzheimer's disease genetics

7 July 2018

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Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila

7 July 2018

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Beta-Arrestins: new roles in regulating heptahelical receptors' functions

7 July 2018

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Interactions between adaptor protein-1 of the clathrin coat and microtubules via type 1a microtubule-associated proteins

7 July 2018

1 reference

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Single nucleotide polymorphism markers for genetic mapping in Drosophila melanogaster

7 July 2018

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Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3

7 July 2018

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Gamma-tubulin complexes and microtubule nucleation

7 July 2018

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EGF receptor and Notch signaling act upstream of Eyeless/Pax6 to control eye specification.

7 July 2018

1 reference

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The Role of presenilins in gamma-secretase activity

7 July 2018

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A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex

7 July 2018

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High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

7 July 2018

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Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

7 July 2018

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7 July 2018

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

7 July 2018

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7 July 2018

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Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

7 July 2018

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Notch and presenilins in vertebrates and invertebrates: implications for neuronal development and degeneration

7 July 2018

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Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz

7 July 2018

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Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism.

7 July 2018

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Notch signaling: cell fate control and signal integration in development

7 July 2018

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7 July 2018

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Presenilin is required for activity and nuclear access of Notch in Drosophila

7 July 2018

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7 July 2018

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The Rap1 GTPase functions as a regulator of morphogenesis in vivo

7 July 2018

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Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

7 July 2018

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The presenilin protein family member SPE-4 localizes to an ER/Golgi derived organelle and is required for proper cytoplasmic partitioning during Caenorhabditis elegans spermatogenesis

7 July 2018

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Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors.

7 July 2018

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NSF binding to GluR2 regulates synaptic transmission

7 July 2018

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LIN-12/Notch signaling: lessons from worms and flies

7 July 2018

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In polarized MDCK cells basolateral vesicles arise from clathrin-gamma-adaptin-coated domains on endosomal tubules

7 July 2018

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Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

7 July 2018

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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

7 July 2018

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The LIN-12/Notch signaling pathway and its regulation

7 July 2018

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Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

7 July 2018

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HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling

7 July 2018

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Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

7 July 2018

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Drying cells for SEM, AFM and TEM by hexamethyldisilazane: a study on hepatic endothelial cells

7 July 2018

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A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing.

7 July 2018

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Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans.

7 July 2018

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Evidence that Spt6p controls chromatin structure by a direct interaction with histones

7 July 2018

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Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development.

7 July 2018

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odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos

7 July 2018

1 reference

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Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras1.

7 July 2018

1 reference

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Multidomain architecture of beta-glycosyl transferases: implications for mechanism of action

7 July 2018

1 reference

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Delta-notch signaling and Drosophila cell fate choice

7 July 2018

1 reference

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Functional domain analysis of glass, a zinc-finger-containing transcription factor in Drosophila

7 July 2018

1 reference

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Mechanisms of drosophila retinal morphogenesis: The virtues of being progressive

7 July 2018

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

7 July 2018

1 reference

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The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells

7 July 2018

1 reference

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shibire, a neurogenic mutant of Drosophila.

7 July 2018

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The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination

7 July 2018

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Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

7 July 2018

1 reference

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Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough.

7 July 2018

1 reference

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Gene regulation in two dimensions: the proneural achaete and scute genes are controlled by combinations of axis-patterning genes through a common intergenic control region

7 July 2018

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Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system

7 July 2018

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Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Epsin potentiates Notch pathway activity in Drosophila and C. elegans

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

In vivo hyaluronan synthesis upon expression of the mammalian hyaluronan synthase gene in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

EGF signaling and ommatidial rotation in the Drosophila eye.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

An EGFR/Ebi/Sno pathway promotes delta expression by inactivating Su(H)/SMRTER repression during inductive notch signaling.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Drosophila nicastrin is essential for the intramembranous cleavage of notch

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

The EGF receptor and notch signaling pathways control the initiation of the morphogenetic furrow during Drosophila eye development.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Polarized dendritic transport and the AP-1 mu1 clathrin adaptor UNC-101 localize odorant receptors to olfactory cilia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

SNARE-dependent signaling at the Drosophila wing margin.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Role of the EGFR/Ras/Raf pathway in specification of photoreceptor cells in the Drosophila retina.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Combinatorial signaling in the specification of unique cell fates

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Drosophila presenilin is required for neuronal differentiation and affects notch subcellular localization and signaling

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

The activity of Drosophila Hairless is required in pupae but not in embryos to inhibit Notch signal transduction.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Establishing primordia in the Drosophila eye-antennal imaginal disc: the roles of decapentaplegic, wingless and hedgehog.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signaling pathway

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

Relationships between complex Delta expression and the specification of retinal cell fates during Drosophila eye development.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456381

A new function for the gamma-tubulin ring complex as a microtubule minus-end cap

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16415372

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1534/GENETICS.104.035170

1 reference

3 August 2017

1 reference

3 August 2017

1 reference