Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals (Q34594647)

3 August 2017

Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals (English)

1 reference

3 August 2017

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1

Mark P Mattson

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3 August 2017

3

Simonetta Camandola

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3 August 2017

Tae Gen Son

2

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3 August 2017

6 August 2007

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3 August 2017

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3 August 2017

5

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3 August 2017

174-186

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3 August 2017

3

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Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

3 August 2017

1 reference

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Protective effect of sulforaphane against dopaminergic cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Design and synthesis of compounds that extend yeast replicative lifespan

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Resveratrol improves health and survival of mice on a high-calorie diet

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Caloric restriction and intermittent fasting: two potential diets for successful brain aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Revenge of the "sit": how lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Exercise and hormesis: activation of cellular antioxidant signaling pathway.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Hormesis/preconditioning mechanisms, the nervous system and aging.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Curcumin activates defensive genes and protects neurons against oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Cereal grains and legumes in the prevention of coronary heart disease and stroke: a review of the literature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Cannabinoid receptor signaling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Cancer biology and hormesis: human tumor cell lines commonly display hormetic (biphasic) dose responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Roles for NF-kappaB in nerve cell survival, plasticity, and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Micronutrients and Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Reactive oxygen species and p38 phosphorylation regulate the protective effect of Delta9-tetrahydrocannabinol in the apoptotic response to NMDA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Cannabinoid receptors and their role in neuroprotection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

New insight into the biosynthesis and regulation of indole compounds in Arabidopsis thaliana

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Oxidation, lipoproteins, and atherosclerosis: which is wrong, the antioxidants or the theory?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Cardiovascular protective effects of resveratrol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Biological properties of curcumin-cellular and molecular mechanisms of action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Fruits and vegetables in the prevention of cellular oxidative damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Cannabinoids: reward, dependence, and underlying neurochemical mechanisms--a review of recent preclinical data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Excitotoxic and Excitoprotective Mechanisms: Abundant Targets for the Prevention and Treatment of Neurodegenerative Disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Paradoxical effects of chemicals in the diet on health

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

How protein kinase C activation protects nerve cells from oxidative stress-induced cell death.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Intake of flavonoids and risk of dementia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

7 July 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Allicin, a major component of garlic, inhibits apoptosis of macrophage in a depleted nutritional state.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Delta9-tetrahydrocannabinol protects hippocampal neurons from excitotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Resveratrol, a natural red wine polyphenol, reduces ischemia-reperfusion-induced spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.2203%2FDOSE-RESPONSE.07-004.MATTSON

Apple juice concentrate prevents oxidative damage and impaired maze performance in aged mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2477698

Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18648607

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2203/DOSE-RESPONSE.07-004.MATTSON

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

18648607