Humanin and age-related diseases: a new link? (Q34631026)

3 August 2017

1 reference

title

Humanin and age-related diseases: a new link? (English)

1 reference

3 August 2017

Zhenwei Gong

1

1 reference

3 August 2017

Emir Tas

series ordinal

2

1 reference

3 August 2017

Radhika Muzumdar

series ordinal

3

1 reference

3 August 2017

publication date

4 December 2014

1 reference

Frontiers in Endocrinology

3 August 2017

published in

1 reference

3 August 2017

volume

5

1 reference

3 August 2017

page(s)

210

1 reference

Metabolism and insulin signaling in common metabolic disorders and inherited insulin resistance

3 August 2017

cites work

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Humanin binds MPP8: mapping interaction sites of the peptide and protein

7 July 2018

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7 July 2018

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7 July 2018

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S14G-humanin inhibits Aβ1-42 fibril formation, disaggregates preformed fibrils, and protects against Aβ-induced cytotoxicity in vitro

7 July 2018

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Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.

7 July 2018

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7 July 2018

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Circulating humanin levels are associated with preserved coronary endothelial function

7 July 2018

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Mortality from ischaemic heart disease by country, region, and age: statistics from World Health Organisation and United Nations

7 July 2018

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Oxidative stress and cancer: an overview

7 July 2018

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A phase I trial of vorinostat and bortezomib in children with refractory or recurrent solid tumors: a Children's Oncology Group phase I consortium study (ADVL0916)

7 July 2018

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Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

7 July 2018

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Pancreatic function, type 2 diabetes, and metabolism in aging

7 July 2018

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Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison

7 July 2018

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Interaction structure of the complex between neuroprotective factor humanin and Alzheimer's β-amyloid peptide revealed by affinity mass spectrometry and molecular modeling

7 July 2018

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Exercise, inflammation and aging

7 July 2018

1 reference

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Humanin, a cytoprotective peptide, is expressed in carotid atherosclerotic [corrected] plaques in humans

7 July 2018

1 reference

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Oxidative stress, mitochondrial dysfunction, and aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin protects cortical neurons from ischemia and reperfusion injury by the increased activity of superoxide dismutase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice

7 July 2018

1 reference

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VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin

7 July 2018

1 reference

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A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice

7 July 2018

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Humanins, the neuroprotective and cytoprotective peptides with antiapoptotic and anti-inflammatory properties.

7 July 2018

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Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion

7 July 2018

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Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury

7 July 2018

1 reference

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Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice

7 July 2018

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Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress

7 July 2018

1 reference

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Immunolocalization of humanin in human sperm and testis.

7 July 2018

1 reference

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Oxidative stress and its role in the pathogenesis of ischaemic stroke

7 July 2018

1 reference

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Humanin: a novel central regulator of peripheral insulin action

7 July 2018

1 reference

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Forecasting the global burden of Alzheimer’s disease

7 July 2018

1 reference

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Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Oxidative stress and metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Full accounting of diabetes and pre-diabetes in the U.S. population in 1988-1994 and 2005-2006

7 July 2018

1 reference

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Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

7 July 2018

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Structural and dynamical studies of Humanin in water and TFE/water mixture: a molecular dynamics simulation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway

7 July 2018

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7 July 2018

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Prevalence of chronic kidney disease in the United States

7 July 2018

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Identification of selectively expressed genes and antigens in CTCL.

7 July 2018

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Chronic inflammation and oxidative stress in human carcinogenesis

7 July 2018

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Oxidative stress as the leading cause of acute myocardial infarction in diabetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin is a novel neuroprotective agent against stroke

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin and colivelin: neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis

7 July 2018

1 reference

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Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1

7 July 2018

1 reference

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Humanin detected in skeletal muscles of MELAS patients: a possible new therapeutic agent.

7 July 2018

1 reference

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Solution structure of humanin, a peptide against Alzheimer's disease-related neurotoxicity

7 July 2018

1 reference

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A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice

7 July 2018

1 reference

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Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Interaction of the spectrin-like repeats of alpha-actinin-4 with humanin peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Increased oxidative stress in obesity and its impact on metabolic syndrome

7 July 2018

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Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

N-Formylated humanin activates both formyl peptide receptor-like 1 and 2

7 July 2018

1 reference

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Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin rescues cortical neurons from prion-peptide-induced apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin peptide suppresses apoptosis by interfering with Bax activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Oxidative stress in Parkinson's disease

7 July 2018

1 reference

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Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevant insults

7 July 2018

1 reference

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Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy

7 July 2018

1 reference

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Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults

7 July 2018

1 reference

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Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

7 July 2018

1 reference

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[Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo

7 July 2018

1 reference

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Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

7 July 2018

1 reference

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A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

7 July 2018

1 reference

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Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein

7 July 2018

1 reference

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Insights into insulin resistance and type 2 diabetes from knockout mouse models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Oxidative stress hypothesis in Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin rescues cultured rat cortical neurons from NMDA-induced toxicity not by NMDA receptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

[Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3β inhibition in a mouse model of intracerebral hemorrhage

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Induction of oxidative stress in kidney

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Protective effects of [Gly14]-Humanin on beta-amyloid-induced PC12 cell death by preventing mitochondrial dysfunction

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

S14G-Humanin ameliorates Abeta25-35-induced behavioral deficits by reducing neuroinflammatory responses and apoptosis in mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Bioactive peptides control receptor for advanced glycated end product-induced elevation of kidney insulin receptor substrate 2 and reduce albuminuria in diabetic mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Proteasome inhibition therapies in childhood cancer.

26 October 2018

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Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action.

26 October 2018

1 reference

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Prevalence of diabetes and impaired fasting glucose in adults in the U.S. population: National Health And Nutrition Examination Survey 1999-2002.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Inhibition of the proteasomal function in chondrocytes down-regulates growth plate chondrogenesis and longitudinal bone growth.

26 October 2018

1 reference

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Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

26 October 2018

1 reference

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Humanin delays apoptosis in K562 cells by downregulation of P38 MAP kinase

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Humanin antagonists: mutants that interfere with dimerization inhibit neuroprotection by Humanin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

A novel rat gene encoding a Humanin-like peptide endowed with broad neuroprotective activity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255622

The secondary structure analysis of a potent Ser14Gly analog of antiAlzheimer peptide, Humanin, by circular dichroism

26 October 2018

1 reference

12 December 2020

Oxidative stress and atherosclerosis

1 reference

12 December 2020

Neuroprotective Peptide humanin inhibits inflammatory response in astrocytes induced by lipopolysaccharide

1 reference

12 December 2020

Oxidative stress and heart failure

1 reference

12 December 2020

Anti-apoptotic factor humanin is expressed in the testis and prevents cell-death in leydig cells during the first wave of spermatogenesis

1 reference

12 December 2020

Identifiers

DOI

10.3389/FENDO.2014.00210

1 reference

3 August 2017

1 reference

3 August 2017

1 reference