Structural mechanisms in NLR inflammasome signaling. (Q34714413)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

review article

1 reference

title

Structural mechanisms in NLR inflammasome signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

Bernhard C Lechtenberg

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Peter D. Mace

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Stefan J Riedl

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

publication date

15 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

Current Opinion in Structural Biology

16 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

17-25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions

16 February 2020

cites work

1 reference

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Mechanisms and functions of inflammasomes

7 July 2018

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Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

7 July 2018

1 reference

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Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes

7 July 2018

1 reference

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Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation

7 July 2018

1 reference

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Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes

7 July 2018

1 reference

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Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

7 July 2018

1 reference

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Biochemical and structural aspects of the ATP-binding domain in inflammasome-forming human NLRP proteins

7 July 2018

1 reference

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Macrophages control innate inflammation

7 July 2018

1 reference

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Crystal structure of NLRC4 reveals its autoinhibition mechanism

7 July 2018

1 reference

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A coupled protein and probe engineering approach for selective inhibition and activity-based probe labeling of the caspases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Apoptosome structure, assembly, and procaspase activation.

7 July 2018

1 reference

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Changes in Apaf-1 Conformation That Drive Apoptosome Assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

The CARD plays a critical role in ASC foci formation and inflammasome signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Phosphorylation of NLRC4 is critical for inflammasome activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Structure and Functional Characterization of the RNA-Binding Element of the NLRX1 Innate Immune Modulator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

NOD-like receptors and the innate immune system: coping with danger, damage and death.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

The death-fold superfamily of homotypic interaction motifs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Structure of the Drosophila Apoptosome at 6.9 Å Resolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Sterile inflammation: sensing and reacting to damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4

7 July 2018

1 reference

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7 July 2018

1 reference

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Pattern recognition receptors and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules

7 July 2018

1 reference

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The Fas-FADD death domain complex structure unravels signalling by receptor clustering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

The Nod-like receptor (NLR) family: a tale of similarities and differences

7 July 2018

1 reference

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The NLR gene family: a standard nomenclature

7 July 2018

1 reference

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Monomer/dimer transition of the caspase-recruitment domain of human Nod1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Crystal structure of the Nod1 caspase activation and recruitment domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Structure of the apoptotic protease-activating factor 1 bound to ADP

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

ICEBERG: a novel inhibitor of interleukin-1beta generation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Kinetic traps in the folding/unfolding of procaspase-1 CARD domain.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268015

Kinetic properties of ASC protein aggregation in epithelial cells

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201319

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inflammasome: putting the pieces together

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201319

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201319

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.SBI.2014.08.011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201319%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

25201319

1 reference