Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9 (Q34727851)

25517468

4 August 2017

title

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9 (English)

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4 August 2017

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2

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11 June 2020

Ryan L Collins

3

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11 June 2020

David Bryder

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11 June 2020

Michael E. Talkowski

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Torsten B Meissner

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17

Chad A Cowan

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11 June 2020

author name string

Pankaj K Mandal

1

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11 June 2020

Christian L Boutwell

5

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11 June 2020

Max Friesen

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11 June 2020

Vladimir Vrbanac

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11 June 2020

Brian S Garrison

8

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11 June 2020

Alexei Stortchevoi

9

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11 June 2020

Kiran Musunuru

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11 June 2020

Harrison Brand

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11 June 2020

Andrew M Tager

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11 June 2020

Todd M Allen

14

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11 June 2020

Derrick J Rossi

16

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11 June 2020

language of work or name

English

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publication date

6 November 2014

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4 August 2017

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11 June 2020

volume

15

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issue

5

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11 June 2020

page(s)

643-652

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describes a project that uses

11 June 2020

1 reference

Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones.

1 reference

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1 reference

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Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

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Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle

7 July 2018

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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CRISPR-Cas systems for editing, regulating and targeting genomes

7 July 2018

1 reference

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Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

7 July 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

7 July 2018

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IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

7 July 2018

1 reference

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

7 July 2018

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An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

7 July 2018

1 reference

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CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

7 July 2018

1 reference

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7 July 2018

1 reference

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DNA targeting specificity of RNA-guided Cas9 nucleases

7 July 2018

1 reference

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7 July 2018

1 reference

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1 reference

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7 July 2018

1 reference

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1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

7 July 2018

1 reference

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7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269831

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

7 July 2018

1 reference

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Dual sgRNAs facilitate CRISPR/Cas9-mediated mouse genome targeting.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269831

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269831

10.1016/J.STEM.2014.10.004

26 October 2018

Identifiers

DOI

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11 June 2020

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11 June 2020

25517468

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