The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway (Q34811541)

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English	The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

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author name string

Jong-In Park

1

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Europe PubMed Central

PubMed publication ID

4 August 2017

Christopher J Strock

2

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Europe PubMed Central

PubMed publication ID

4 August 2017

Douglas W Ball

3

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Europe PubMed Central

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4 August 2017

Barry D Nelkin

4

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Europe PubMed Central

PubMed publication ID

4 August 2017

language of work or name

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publication date

1 January 2003

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Europe PubMed Central

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4 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

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4 August 2017

23

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Europe PubMed Central

PubMed publication ID

4 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

543-554

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

The INK4a/ARF network in tumour suppression

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8 July 2018

Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells

1 reference

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8 July 2018

Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells

1 reference

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8 July 2018

Regulation of the p53 pathway by Ras, the plot thickens

1 reference

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8 July 2018

Analysis of the transcriptional program induced by Raf in epithelial cells

1 reference

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8 July 2018

Regulation of the G2/M transition by p53.

1 reference

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8 July 2018

p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

1 reference

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8 July 2018

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

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p53-independent functions of the p19(ARF) tumor suppressor

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Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

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Leukemia-inhibitory factor-neuroimmune modulator of endocrine function

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Mitogenic conversion of transforming growth factor-beta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer.

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Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

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STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells .

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8 July 2018

STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP.

1 reference

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8 July 2018

Stat3 as an oncogene

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8 July 2018

Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade.

1 reference

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Creation of human tumour cells with defined genetic elements

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Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

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8 July 2018

The levels of leukemia inhibitory factor mRNA in a Schwann cell line are regulated by multiple second messenger pathways

1 reference

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Critical role for STAT3 in murine pituitary adrenocorticotropin hormone leukemia inhibitory factor signaling

1 reference

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8 July 2018

Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells

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8 July 2018

Activation of signal transducers and activators of transcription 1 and 3 by leukemia inhibitory factor, oncostatin-M, and interferon-gamma in adipocytes

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8 July 2018

Senescence of human fibroblasts induced by oncogenic Raf.

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8 July 2018

Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells

1 reference

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8 July 2018

Leukemia inhibitory factor modulates interleukin-1beta-induced activation of the hypothalamo-pituitary-adrenal axis

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A simplified system for generating recombinant adenoviruses

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8 July 2018

Activated Raf-1 causes growth arrest in human small cell lung cancer cells

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Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.

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Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

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p53 tumor-suppressor gene: clues to molecular carcinogenesis

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8 July 2018

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151536

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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Activation of acidic sphingomyelinase and protein kinase C zeta is required for IL-1 induction of LIF mRNA in a Schwann cell line

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Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase

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Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression

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Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

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The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

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Ret gene silencing is associated with Raf-1-induced medullary thyroid carcinoma cell differentiation.

1 reference

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8 July 2018

Involvement of protein kinase C during activation of the mitogen-activated protein kinase cascade by leukemia inhibitory factor. Evidence for participation of multiple signaling pathways.

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Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

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In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

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Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells

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https://pubmed.ncbi.nlm.nih.gov/12509453

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12509453

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12509453

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Identifiers

10.1128/MCB.23.2.543-554.2003

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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