Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis (Q34859485)

4 August 2017

title

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis (English)

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4 August 2017

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J Dennemärker

1

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4 August 2017

T Lohmüller

2

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4 August 2017

J Mayerle

3

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4 August 2017

M Tacke

4

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4 August 2017

M M Lerch

5

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4 August 2017

L M Coussens

6

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4 August 2017

C Peters

7

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4 August 2017

T Reinheckel

8

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4 August 2017

language of work or name

English

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publication date

21 December 2009

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4 August 2017

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4 August 2017

volume

29

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4 August 2017

issue

11

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4 August 2017

page(s)

1611-1621

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Design of selective Cathepsin inhibitors

4 August 2017

cites work

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8 July 2018

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Tumor microenvironment and angiogenesis

8 July 2018

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Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment

8 July 2018

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8 July 2018

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Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation.

8 July 2018

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The other side of MMPs: protective roles in tumor progression

8 July 2018

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Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.

8 July 2018

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Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

8 July 2018

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Paradoxical roles of the immune system during cancer development

8 July 2018

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The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

8 July 2018

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The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.

8 July 2018

1 reference

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Cathepsin L is required for endothelial progenitor cell-induced neovascularization

8 July 2018

1 reference

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Cysteine cathepsins in human cancer

8 July 2018

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Friends or foes - bipolar effects of the tumour stroma in cancer

8 July 2018

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Proteases, extracellular matrix, and cancer: a workshop of the path B study section

8 July 2018

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Senescence-initiated reversal of drug resistance: specific role of cathepsin L.

8 July 2018

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Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

8 July 2018

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8 July 2018

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Basement membranes: structure, assembly and role in tumour angiogenesis

8 July 2018

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Analysis of proteins with caseinolytic activity in a human stratum corneum extract revealed a yet unidentified cysteine protease and identified the so-called "stratum corneum thiol protease" as cathepsin l2.

8 July 2018

1 reference

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The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling

8 July 2018

1 reference

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

8 July 2018

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The microenvironment of the tumour-host interface

8 July 2018

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MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

8 July 2018

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Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and perturbation of hair follicle cycling

8 July 2018

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Secreted cathepsin L generates endostatin from collagen XVIII

8 July 2018

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Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

8 July 2018

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8 July 2018

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Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.

8 July 2018

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8 July 2018

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Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

8 July 2018

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De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent

21 January 2018

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Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Emerging roles of proteases in tumour suppression

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.466

Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Signaling on the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Genomic Analysis Defines a Cancer-Specific Gene Expression Signature for Human Squamous Cell Carcinoma and Distinguishes Malignant Hyperproliferation from Benign Hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.466

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Dimensions Publication ID

4 August 2017

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4 August 2017

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