Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells (Q34982241)

5 August 2017

Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells (English)

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5 August 2017

B Z Carter

1

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5 August 2017

D H Mak

2

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5 August 2017

R Woessner

3

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5 August 2017

S Gross

4

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5 August 2017

W D Schober

5

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5 August 2017

Z Estrov

6

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5 August 2017

H Kantarjian

7

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5 August 2017

M Andreeff

8

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5 August 2017

21 May 2009

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5 August 2017

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5 August 2017

23

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5 August 2017

10

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5 August 2017

1755-1762

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https://scigraph.springernature.com/pub.10.1038/leu.2009.101

5 August 2017

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cites work

Microtubules in apoptosis induction: are they necessary?

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Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Development of new cancer therapeutic agents targeting mitosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Microtubules as a target for anticancer drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Death receptor-dependent and -independent pathways in anticancer drug-induced apoptosis of breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

8 July 2018

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Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Effect of interleukin-1 beta converting enzyme inhibitor on acute myelogenous leukemia progenitor proliferation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593228

Chronic myelogenous leukemia molecular signature.

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.101

Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.101

Apoptosis induced by low-dose paclitaxel is associated with p53 upregulation in nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.101

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.101

p53 status and the efficacy of cancer therapy in vivo

21 January 2018

1 reference

12 December 2020

All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5

1 reference

12 December 2020

Molecular phylogeny of the kinesin family of microtubule motor proteins

1 reference

12 December 2020

Activation of Hex and mEg5 by retroviral insertion may contribute to mouse B-cell leukemia

1 reference

12 December 2020

XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2009.101

1 reference

Dimensions Publication ID

5 August 2017

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1 reference

5 August 2017

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