Solution NMR insights into docking interactions involving inactive ERK2 (Q35012791)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21449613%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Solution NMR insights into docking interactions involving inactive ERK2 (English)

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27 January 2020

6

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27 January 2020

Pengyu Ren

7

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27 January 2020

Ranajeet Ghose

9

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27 January 2020

author name string

Andrea Piserchio

1

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27 January 2020

Mangalika Warthaka

2

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27 January 2020

Ashwini K Devkota

3

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27 January 2020

Tamer S Kaoud

4

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27 January 2020

Sunbae Lee

5

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27 January 2020

Kevin N Dalby

8

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27 January 2020

language of work or name

English

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publication date

19 April 2011

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27 January 2020

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27 January 2020

volume

50

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27 January 2020

issue

18

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27 January 2020

page(s)

3660-3672

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Assignment of backbone resonances in a eukaryotic protein kinase - ERK2 as a representative example

27 January 2020

cites work

1 reference

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A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach

8 July 2018

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The third conformation of p38α MAP kinase observed in phosphorylated p38α and in solution

8 July 2018

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Protein kinases: evolution of dynamic regulatory proteins

8 July 2018

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Dynamics connect substrate recognition to catalysis in protein kinase A

8 July 2018

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Phosphorylation of the transcription factor Ets-1 by ERK2: rapid dissociation of ADP and phospho-Ets-1.

8 July 2018

1 reference

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Defining the conserved internal architecture of a protein kinase.

8 July 2018

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Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes.

8 July 2018

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Interface analysis of the complex between ERK2 and PTP-SL

8 July 2018

1 reference

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Substrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifs

8 July 2018

1 reference

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Allosteric cooperativity in protein kinase A.

8 July 2018

1 reference

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Unique MAP Kinase binding sites

8 July 2018

1 reference

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Expanding the repertoire of an ERK2 recruitment site: cysteine footprinting identifies the D-recruitment site as a mediator of Ets-1 binding.

8 July 2018

1 reference

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Protein backbone chemical shifts predicted from searching a database for torsion angle and sequence homology

8 July 2018

1 reference

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The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity

8 July 2018

1 reference

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Networks for the allosteric control of protein kinases

8 July 2018

1 reference

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Docking interactions in protein kinase and phosphatase networks

8 July 2018

1 reference

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A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases

8 July 2018

1 reference

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Targeting the ERK signaling pathway in cancer therapy

8 July 2018

1 reference

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MAPK signal specificity: the right place at the right time

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103835

Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3.

8 July 2018

1 reference

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The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

8 July 2018

1 reference

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The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network

8 July 2018

1 reference

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The MAPK signalling pathways and colorectal cancer

8 July 2018

1 reference

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Src family kinases, key regulators of signal transduction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103835

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

8 July 2018

1 reference

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Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

8 July 2018

1 reference

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Pharmacological inhibitors of the ERK signaling pathway: application as anticancer drugs

8 July 2018

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A Bipartite Mechanism for ERK2 Recognition by Its Cognate Regulators and Substrates

8 July 2018

1 reference

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Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain

8 July 2018

1 reference

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Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1

8 July 2018

1 reference

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An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors

8 July 2018

1 reference

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8 July 2018

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PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

8 July 2018

1 reference

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

8 July 2018

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Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange

8 July 2018

1 reference

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A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission

8 July 2018

1 reference

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Signal transduction by the JNK group of MAP kinases

8 July 2018

1 reference

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Docking domains and substrate-specificity determination for MAP kinases

8 July 2018

1 reference

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A conserved docking motif in MAP kinases common to substrates, activators and regulators

8 July 2018

1 reference

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Signal transduction by MAP kinase cascades in budding yeast

8 July 2018

1 reference

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TROSY in triple-resonance experiments: new perspectives for sequential NMR assignment of large proteins

8 July 2018

1 reference

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Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103835

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

8 July 2018

1 reference

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Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

8 July 2018

1 reference

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

8 July 2018

1 reference

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Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib

8 July 2018

1 reference

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The anti-apoptotic protein PEA-15 is a tight binding inhibitor of ERK1 and ERK2, which blocks docking interactions at the D-recruitment site.

25 October 2018

1 reference

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Properties and regulation of a transiently assembled ERK2.Ets-1 signaling complex.

25 October 2018

1 reference

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NMR characterization of kinase p38 dynamics in free and ligand-bound forms

25 October 2018

1 reference

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Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry

25 October 2018

1 reference

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PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation

25 October 2018

1 reference

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The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases

25 October 2018

1 reference

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Purification of a model substrate for transcription factor phosphorylation by ERK2.

25 October 2018

1 reference

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A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1.

25 October 2018

1 reference

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Characterizing the use of perdeuteration in NMR studies of large proteins: 13C, 15N and 1H assignments of human carbonic anhydrase II.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103835

The ETS-domain transcription factor family

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21449613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Docking interactions induce exposure of activation loop in the MAP kinase ERK2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21449613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1-13C amino acid selective labeling in a 2H15N background for NMR studies of large proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21449613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI2000559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21449613%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21449613%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

21449613

1 reference