Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease. (Q35012792)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Megan K. Levings

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

A Y Wang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

11 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

Clinical and Experimental Immunology

12 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

159

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

109-119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes

12 February 2020

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Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

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25 October 2018

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Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t.

25 October 2018

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Comment on "Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta".

25 October 2018

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Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells

25 October 2018

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The macrophage mannose receptor induces IL-17 in response to Candida albicans.

25 October 2018

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25 October 2018

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In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

25 October 2018

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Human Th17 cells: are they different from murine Th17 cells?

25 October 2018

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Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

25 October 2018

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Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

25 October 2018

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation.

25 October 2018

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Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

25 October 2018

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Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

25 October 2018

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Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

25 October 2018

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CD4+ T-regulatory cells: toward therapy for human diseases.

25 October 2018

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Th17 cells in human disease.

25 October 2018

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Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

25 October 2018

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Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

25 October 2018

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The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

25 October 2018

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Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat

25 October 2018

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Cyclosporin A inhibits the production of IL-17 by memory Th17 cells from healthy individuals and patients with rheumatoid arthritis

25 October 2018

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TH17 cells in development: an updated view of their molecular identity and genetic programming

25 October 2018

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The biological functions of T helper 17 cell effector cytokines in inflammation

25 October 2018

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Th17 cell differentiation: the long and winding road

25 October 2018

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

25 October 2018

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Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

25 October 2018

1 reference

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

25 October 2018

1 reference

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The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

25 October 2018

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

25 October 2018

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Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

25 October 2018

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Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

25 October 2018

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Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells

25 October 2018

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STAT3 mutations in the hyper-IgE syndrome

25 October 2018

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Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

25 October 2018

1 reference

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Distinct regulation of interleukin-17 in human T helper lymphocytes

25 October 2018

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The clinical role of IL-23p19 in patients with rheumatoid arthritis.

25 October 2018

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Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

25 October 2018

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

25 October 2018

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Phenotypic and functional features of human Th17 cells

25 October 2018

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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

25 October 2018

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Increased interleukin-17 production both in helper T cell subset Th17 and CD4-negative T cells in human immunodeficiency virus infection

25 October 2018

1 reference

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Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators

25 October 2018

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T(H)-17 cells in the circle of immunity and autoimmunity

25 October 2018

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The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

25 October 2018

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A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

25 October 2018

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

25 October 2018

1 reference

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Association of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G).

25 October 2018

1 reference

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

25 October 2018

1 reference

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

25 October 2018

1 reference

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Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice

25 October 2018

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kappaB- and p38 MAPK-dependent signalling pathways.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Cerebrospinal fluid and serum levels and intrathecal production of active matrix metalloproteinase-9 (MMP-9) as markers of disease activity in patients with multiple sclerosis.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Transforming growth factor-beta induces development of the T(H)17 lineage

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Interleukin-17 family members and inflammation

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Tax protein of human T-cell leukaemia virus type 1 induces interleukin 17 gene expression in T cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Upregulation of interleukin-12 and -17 in active inflammatory bowel disease

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Increased expression of interleukin 17 in inflammatory bowel disease

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Interleukin 17 modulates the immune response to vaccinia virus infection

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

High in vivo expression of interleukin-17 receptor in synovial endothelial cells and chondrocytes from arthritis patients.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Follicular homing T helper (Th) cells and the Th1/Th2 paradigm

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Lineage commitment in the immune system: the T helper lymphocyte grows up.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Interleukin-17 and its receptor

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Functional diversity of helper T lymphocytes

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810379

High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

25 October 2018

1 reference

12 December 2020

Porphyromonas gingivalis antigen preferentially stimulates T cells to express IL-17 but not receptor activator of NF-kappaB ligand in vitro

1 reference

12 December 2020

Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17

1 reference

12 December 2020

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

12 December 2020

Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection

1 reference

12 December 2020

The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4

1 reference

12 December 2020

Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells

1 reference

12 December 2020

IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood

1 reference

12 December 2020

Autocrine regulation of IL-21 production in human T lymphocytes

1 reference

12 December 2020

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

1 reference

12 December 2020

Interleukin-17 augments tumor necrosis factor-alpha-induced granulocyte and granulocyte/macrophage colony-stimulating factor release from human colonic myofibroblasts

1 reference

12 December 2020

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

1 reference

12 December 2020

A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease

1 reference

12 December 2020

Drug evaluation: apilimod, an oral IL-12/IL-23 inhibitor for the treatment of autoimmune diseases and common variable immunodeficiency

1 reference

12 December 2020

T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity

1 reference

12 December 2020

Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation

1 reference

12 December 2020

Functional relevance of the IL-23-IL-17 axis in lungs in vivo

1 reference

12 December 2020

The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells

1 reference

12 December 2020

B cell chemoattractant CXCL13 is preferentially expressed by human Th17 cell clones

1 reference

12 December 2020

Human immunodeficiency: connecting STAT3, Th17 and human mucosal immunity

1 reference

12 December 2020

TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells.

1 reference

12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

1 reference

12 December 2020

10.1111/J.1365-2249.2009.04037.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19912252%20AND%20SRC:MED&resulttype=core&format=json

release_chcfe5yrgrgxlkzrc43ciwgcl4

12 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/chcfe5yrgrgxlkzrc43ciwgcl4

24 November 2022

mapped directly with Wikidata item

0 references

1 reference