ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2. (Q35064898)

6 August 2017

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2. (English)

1 reference

6 August 2017

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646266%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

René Riedel

10

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1 June 2020

Joachim R. Grün

11

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1 June 2020

Mir-Farzin Mashreghi

15

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1 June 2020

Andreas Hutloff

16

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1 June 2020

14

Andreas Radbruch

1 reference

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1 June 2020

author name string

Jan P Weber

1

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1 June 2020

Franziska Fuhrmann

2

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1 June 2020

Randi K Feist

3

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1 June 2020

Maysun S Al Baz

5

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1 June 2020

Lea-Jean Gentz

6

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1 June 2020

Dana Vu Van

7

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1 June 2020

Hans W Mages

8

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1 June 2020

Claudia Haftmann

9

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1 June 2020

Wolfgang Schuh

12

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1 June 2020

Richard A Kroczek

13

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1 June 2020

language of work or name

English

0 references

publication date

2 February 2015

1 reference

Journal of Experimental Medicine

6 August 2017

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1 June 2020

volume

212

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1 June 2020

page(s)

217-233

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1 June 2020

issue

2

1 reference

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A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells

1 June 2020

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The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells

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B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen

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Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development

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The unique features of follicular T cell subsets

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The good, the bad and the ugly - TFH cells in human health and disease

8 July 2018

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Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype

8 July 2018

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FOXO transcription factors throughout T cell biology

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Follicular helper T cells in immunity and systemic autoimmunity

8 July 2018

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Krüppel-like factors in lymphocyte biology

8 July 2018

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Molecular programming of B cell memory

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Controlled gene expression in primary Lgr5 organoid cultures

8 July 2018

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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

8 July 2018

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

8 July 2018

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Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

8 July 2018

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Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding

8 July 2018

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Follicular helper CD4 T cells (TFH)

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Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction

8 July 2018

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Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

8 July 2018

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In vivo regulation of Bcl6 and T follicular helper cell development

8 July 2018

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Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.

8 July 2018

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8 July 2018

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Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS

8 July 2018

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Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

8 July 2018

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

8 July 2018

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Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

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Kruppel-like factor 2 regulates thymocyte and T-cell migration

8 July 2018

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CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

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The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo

8 July 2018

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Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

8 July 2018

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Constitutive expression of the B7h ligand for inducible costimulator on naive B cells is extinguished after activation by distinct B cell receptor and interleukin 4 receptor-mediated pathways and can be rescued by CD40 signaling

8 July 2018

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ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells

8 July 2018

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ICOS is essential for effective T-helper-cell responses

8 July 2018

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ICOS is critical for CD40-mediated antibody class switching

8 July 2018

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Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

8 July 2018

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Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.

8 July 2018

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

8 July 2018

1 reference

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Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa

8 July 2018

1 reference

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Expression and functional significance of an additional ligand for CTLA-4.

8 July 2018

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Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

8 July 2018

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Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

8 July 2018

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Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.

8 July 2018

1 reference

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T-follicular helper cells survive as long-term memory cells.

27 September 2018

1 reference

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The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.

27 September 2018

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Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis

27 September 2018

1 reference

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FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase

27 September 2018

1 reference

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ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse.

27 September 2018

1 reference

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Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

27 September 2018

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Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

27 September 2018

1 reference

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ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells.

27 September 2018

1 reference

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Transcriptional regulation of th2 differentiation by inducible costimulator.

27 September 2018

1 reference

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Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection

27 September 2018

1 reference

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B cell development under the condition of allelic inclusion.

27 September 2018

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Structure and dynamics of a primordial catalytic fold generated by in vitro evolution

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20141432

Abatacept Limits Breach of Self-Tolerance in a Murine Model of Arthritis via Effects on the Generation of T Follicular Helper Cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20141432

Antigen-specific T lymphocytes regulate lipopolysaccharide-induced apoptosis of dendritic cells in vivo

21 January 2018

1 reference

12 December 2020

ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling

1 reference

12 December 2020

Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs

1 reference

12 December 2020

Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription

1 reference

12 December 2020

Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20141432

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646266%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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1 June 2020

1 reference

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