Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses (Q35072158)

6 August 2017

title

Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses (English)

1 reference

6 August 2017

Gregory F Wu

1

1 reference

6 August 2017

Evann Corbo

2

1 reference

6 August 2017

Michelle Schmidt

3

1 reference

6 August 2017

Jennifer E Smith-Garvin

4

1 reference

6 August 2017

Matthew J Riese

5

1 reference

6 August 2017

Martha S Jordan

6

1 reference

6 August 2017

Terri M Laufer

7

1 reference

6 August 2017

Eric J Brown

8

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6 August 2017

Jonathan S Maltzman

9

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6 August 2017

language of work or name

English

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publication date

7 June 2011

1 reference

European Journal of Immunology

6 August 2017

published in

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6 August 2017

volume

41

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6 August 2017

issue

7

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6 August 2017

page(s)

2064-2073

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Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells

6 August 2017

cites work

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8 July 2018

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Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis.

8 July 2018

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The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells

8 July 2018

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C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

8 July 2018

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Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

8 July 2018

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Antiviral CD4+ memory T cells are IL-15 dependent

8 July 2018

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Functional hierarchy of the N-terminal tyrosines of SLP-76.

8 July 2018

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Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection

8 July 2018

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Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis

8 July 2018

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Jurkat T cells and development of the T-cell receptor signalling paradigm

8 July 2018

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Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2

8 July 2018

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Adaptors as central mediators of signal transduction in immune cells

8 July 2018

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Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

8 July 2018

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Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

8 July 2018

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Transgenic analysis of thymocyte signal transduction

8 July 2018

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Differential role of SLP-76 domains in T cell development and function

8 July 2018

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Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

8 July 2018

1 reference

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Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways

8 July 2018

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Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

8 July 2018

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Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

8 July 2018

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Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

8 July 2018

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Essential role of LAT in T cell development

8 July 2018

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

8 July 2018

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Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

8 July 2018

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Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor

8 July 2018

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Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76.

27 September 2018

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Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing.

27 September 2018

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Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine

27 September 2018

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TCR signals mediated by Src family kinases are essential for the survival of naive T cells

27 September 2018

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A LAT mutation that inhibits T cell development yet induces lymphoproliferation

27 September 2018

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Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Suppression of thymic development by the dominant-negative form of Gads.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Experimental autoimmune encephalomyelitis in NF-kappa B-deficient mice:roles of NF-kappa B in the activation and differentiation of autoreactive T cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124603

Long-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lck

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FEJI.201040809

Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker

21 January 2018

1 reference

12 December 2020

The Src homology 2 domain-containing leukocyte protein of 76-kDa adaptor links integrin ligation with p44/42 MAPK phosphorylation and podosome distribution in murine dendritic cells

1 reference

12 December 2020

Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses

1 reference

12 December 2020

Experimental autoimmune encephalomyelitis (EAE)

1 reference

12 December 2020

Differential requirement for SLP-76 domains in T cell development and function

1 reference

12 December 2020

Identifiers

DOI

10.1002/EJI.201040809

1 reference

6 August 2017

1 reference

6 August 2017

1 reference