Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent (Q35078672)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20499347%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent (English)

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3 February 2020

1

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3 February 2020

author name string

Shan Chen

2

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3 February 2020

Tao Yang

3

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3 February 2020

Brian Dawson

4

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3 February 2020

Elda Munivez

5

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3 February 2020

Terry Bertin

6

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3 February 2020

Brendan Lee

7

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3 February 2020

publication date

1 October 2010

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Journal of Bone and Mineral Research

3 February 2020

published in

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3 February 2020

volume

25

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3 February 2020

issue

10

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3 February 2020

page(s)

2175-2183

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Alteration of Notch signaling in skeletal development and disease

3 February 2020

cites work

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Direct inhibition of the NOTCH transcription factor complex

8 July 2018

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Paget disease: when to treat and when not to treat

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Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation

8 July 2018

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The canonical Notch signaling pathway: unfolding the activation mechanism

8 July 2018

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Notch signaling contributes to the pathogenesis of human osteosarcomas

8 July 2018

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Mutation of the fucose-specific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine

8 July 2018

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8 July 2018

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The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis

8 July 2018

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Osteosarcoma development and stem cell differentiation

8 July 2018

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Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

8 July 2018

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A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis

8 July 2018

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Critical role of notch signaling in osteosarcoma invasion and metastasis

8 July 2018

1 reference

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Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity

8 July 2018

1 reference

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Notch inhibits osteoblast differentiation and causes osteopenia

8 July 2018

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Gamma-secretase inhibition and modulation for Alzheimer's disease

8 July 2018

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Sclerosing bone disorders

8 July 2018

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Dimorphic effects of Notch signaling in bone homeostasis.

8 July 2018

1 reference

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Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

8 July 2018

1 reference

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Wnt/Notch signalling and information processing during development.

8 July 2018

1 reference

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Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis

8 July 2018

1 reference

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Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.

8 July 2018

1 reference

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Notch signaling pathway and tissue engineering.

8 July 2018

1 reference

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Abnormal vertebral segmentation and the notch signaling pathway in man.

8 July 2018

1 reference

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The CBF1-independent Notch1 signal pathway activates human c-myc expression partially via transcription factor YY1.

8 July 2018

1 reference

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The genetics of low-density lipoprotein receptor-related protein 5 in bone: a story of extremes

8 July 2018

1 reference

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Insights into material and structural basis of bone fragility from diseases associated with fractures: how determinants of the biomechanical properties of bone are compromised by disease.

8 July 2018

1 reference

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Notch signalling: a simple pathway becomes complex

8 July 2018

1 reference

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Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

8 July 2018

1 reference

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Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

8 July 2018

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Notch1 augments NF-kappaB activity by facilitating its nuclear retention

8 July 2018

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Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation.

8 July 2018

1 reference

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BMP4-dependent expression of Xenopus Grainyhead-like 1 is essential for epidermal differentiation

8 July 2018

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Osteosarcoma occurring in osteogenesis imperfecta

8 July 2018

1 reference

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Notch signaling controls multiple steps of pancreatic differentiation

8 July 2018

1 reference

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CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

8 July 2018

1 reference

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The notch intracellular domain can function as a coactivator for LEF-1

8 July 2018

1 reference

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Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Increased bone formation in osteocalcin-deficient mice.

8 July 2018

1 reference

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Osteosarcoma associated with osteopoikilosis

8 July 2018

1 reference

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Skeletal fluorosis from instant tea.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast

27 September 2018

1 reference

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A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126919

Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1

27 September 2018

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Recovery from skeletal fluorosis (an enigmatic, American case)

9 December 2018

1 reference

12 December 2020

Osteosclerosis due to endemic fluorosis

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12 December 2020

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

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12 December 2020

Osteosarcoma arising in a femur with melorheostosis and osteopathia striata

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12 December 2020

Identifiers

DOI

10.1002/JBMR.115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20499347%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

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3 February 2020

PubMed publication ID

20499347

1 reference