Hyperglycemic Ins2AkitaLdlr⁻/⁻ mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease (Q35107280)

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English	Hyperglycemic Ins2AkitaLdlr⁻/⁻ mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease	scientific article

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Hyperglycemic Ins2AkitaLdlr⁻/⁻ mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease (English)

1 reference

Europe PubMed Central

6 August 2017

1 reference

based on heuristic

inferred from title

atherosclerosis

1 reference

based on heuristic

inferred from title

Changcheng Zhou

1

object named as

Changcheng Zhou

1 reference

Europe PubMed Central

6 August 2017

author name string

Brian Pridgen

2

1 reference

Europe PubMed Central

6 August 2017

Nakesha King

3

1 reference

Europe PubMed Central

6 August 2017

Jinxian Xu

4

1 reference

Europe PubMed Central

6 August 2017

Jan L Breslow

5

1 reference

Europe PubMed Central

6 August 2017

publication date

23 May 2011

1 reference

Europe PubMed Central

6 August 2017

Journal of Lipid Research

1 reference

Europe PubMed Central

6 August 2017

52

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Europe PubMed Central

6 August 2017

8

1 reference

Europe PubMed Central

6 August 2017

1483-1493

1 reference

Europe PubMed Central

6 August 2017

Global analysis of the eukaryotic pathways and networks regulated by Salmonella typhimurium in mouse intestinal infection in vivo

1 reference

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9 July 2018

Liver x receptor signaling pathways and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

1 reference

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9 July 2018

Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice

1 reference

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9 July 2018

Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Type 1 diabetes, hyperglycaemia, and the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

1 reference

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9 July 2018

Recipes for creating animal models of diabetic cardiovascular disease

1 reference

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9 July 2018

Approaches to prevention of cardiovascular complications and events in diabetes mellitus

1 reference

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Pathway analysis identifies perturbation of genetic networks induced by butyrate in a bovine kidney epithelial cell line

1 reference

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PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine

1 reference

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9 July 2018

Type 1 diabetes and coronary artery disease

1 reference

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The immune response in atherosclerosis: a double-edged sword

1 reference

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9 July 2018

Diabetic vascular disease: an experimental objective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Liver X receptors as integrators of metabolic and inflammatory signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Protein sensors for membrane sterols

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9 July 2018

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

A network-based analysis of systemic inflammation in humans

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Report of the National Heart, Lung, and Blood Institute-National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Cardiovascular Complications of Type 1 Diabetes Mellitus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Inflammation in atherosclerosis

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Genotoxicity of streptozotocin

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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9 July 2018

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

1 reference

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9 July 2018

Diabetes and endothelial dysfunction: a clinical perspective

1 reference

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9 July 2018

Atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

1 reference

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9 July 2018

A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse

1 reference

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9 July 2018

Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia

1 reference

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9 July 2018

Mapping of murine diabetogenic gene mody on chromosome 7 at D7Mit258 and its involvement in pancreatic islet and beta cell development during the perinatal period

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3137013

9 July 2018

Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes

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9 July 2018

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice

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9 July 2018

Magnitude and determinants of coronary artery disease in juvenile-onset, insulin-dependent diabetes mellitus

1 reference

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Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis

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9 July 2018

Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice

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GSEA-P: a desktop application for Gene Set Enrichment Analysis.

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Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.

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27 September 2018

Proinsulin lacking the A7-B7 disulfide bond, Ins2Akita, tends to aggregate due to the exposed hydrophobic surface.

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Induction of atherosclerosis by low-fat, semisynthetic diets in LDL receptor-deficient C57BL/6J and FVB/NJ mice: comparison of lesions of the aortic root, brachiocephalic artery, and whole aorta (en face measurement).

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Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse

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Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-α secretion in Abca1-deficient macrophages

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Mouse Models of Atherosclerosis

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12 December 2020

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Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

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https://pubmed.ncbi.nlm.nih.gov/21606463

12 December 2020

based on heuristic

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The burden of mortality attributable to diabetes: realistic estimates for the year 2000

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https://pubmed.ncbi.nlm.nih.gov/21606463

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Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606463

12 December 2020

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Identifiers

10.1194/JLR.M014092

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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