Genealogy, expression, and cellular function of transforming growth factor-β (Q35119392)

6 August 2017

1 reference

title

Genealogy, expression, and cellular function of transforming growth factor-beta (English)

1 reference

6 August 2017

Genealogy, expression, and cellular function of transforming growth factor-β (English)

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

regulation of gene expression

29 December 2023

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12725873

physiologic neovascularization

29 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12725873

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

29 December 2023

author name string

R. Govinden

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12725873

29 December 2023

K. D. Bhoola

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12725873

29 December 2023

language of work or name

1 reference

1 May 2003

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full work available at URL

6 August 2017

https://api.elsevier.com/content/article/PII:S0163725803000354?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

https://api.elsevier.com/content/article/PII:S0163725803000354?httpAccept=text/plain

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

Pharmacology & Therapeutics

29 December 2023

published in

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6 August 2017

98

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6 August 2017

2

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6 August 2017

257-265

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Cellular transformation by coordinated action of three peptide growth factors from human platelets

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Signal transduction by members of the transforming growth factor-beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Smads as transcriptional co-modulators

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta receptors and actions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF beta in prostate cancer: a growth inhibitor that can enhance tumorigenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Transcriptional regulation of the transforming growth factor beta 1 promoter by v-src gene products is mediated through the AP-1 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Rat mesangial cell hypertrophy in response to transforming growth factor-beta 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Genomic analysis of metastasis reveals an essential role for RhoC

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

c-Jun inhibits transforming growth factor beta-mediated transcription by repressing Smad3 transcriptional activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Smads: transcriptional activators of TGF-beta responses

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Mechanisms of transforming growth factor-beta receptor endocytosis and intracellular sorting differ between fibroblasts and epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Purification and initial characterization of a type beta transforming growth factor from human placenta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Basic fibroblast growth factor and transforming growth factor beta-1: synergistic mediators of angiogenesis in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Transforming growth factor beta receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-beta binding protein-1 that mediates bonding to the latent transforming growth factor-beta1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in-situ and invasive carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

The latent transforming growth factor-beta-binding protein-1 promotes in vitro differentiation of embryonic stem cells into endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Hereditary hemorrhagic telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta isoform release and activation during in vitro bronchial epithelial wound repair

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Elevated plasma levels of TGF-β1 in patients with invasive prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Regulation of immune responses by TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Smads bind directly to the Jun family of AP-1 transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Positive and negative regulation of type II TGF-beta receptor signal transduction by autophosphorylation on multiple serine residues

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

The transforming growth factor-beta family

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Differential roles of JNK and Smad2 signaling pathways in the inhibition of c-Myc-induced cell death by TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Latent transforming growth factor-beta: structural features and mechanisms of activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Molecular portraits of human breast tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Mechanisms of angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Regulation of endothelial cell growth, architecture, and matrix synthesis by TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Cloning and characterization of a human type II receptor for bone morphogenetic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-beta(1) in transformed keratinocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Transgenic models for the study of prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad suppresses early Smad-driven gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta receptors and signalling mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Mechanism of activation of the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Expression of TGF-beta signaling genes in the normal, premalignant, and malignant human trophoblast: loss of smad3 in choriocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900035-4

7 January 2021

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness

12

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https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

Establishment of lipopolysaccharide-dependent nuclear factor kappa B activation in a cell-free system

29 December 2023

64

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels

29 December 2023

69

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https://api.crossref.org/works/10.1016/S0163-7258(03)00035-4

29 December 2023

Identifiers

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6 August 2017

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