The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation (Q35142283)

6 August 2017

title

The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation (English)

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6 August 2017

1 reference

Abdollah Ghasemian

8

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Serena Bonin

object named as

Serena Bonin

9

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Giorgio Stanta

object named as

Giorgio Stanta

11

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Miran Skrap

10

object named as

Miran Skrap

1 reference

6 August 2017

7

Tamara Ius

1 reference

6 August 2017

author name string

Ramiro Mendoza-Maldonado

1

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6 August 2017

Valentina Faoro

2

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6 August 2017

Sailesh Bajpai

3

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6 August 2017

Matteo Berti

4

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6 August 2017

Federico Odreman

5

1 reference

6 August 2017

Marco Vindigni

6

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6 August 2017

Alessandro Vindigni

12

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6 August 2017

publication date

13 July 2011

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6 August 2017

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6 August 2017

volume

10

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6 August 2017

page(s)

83

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RECQL1 and WRN proteins are potential therapeutic targets in head and neck squamous cell carcinoma

6 August 2017

cites work

1 reference

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Molecular diagnostics of gliomas

13 July 2018

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Probing the structural basis of RecQ helicase function

13 July 2018

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RecQL1 DNA repair helicase: A potential tumor marker and therapeutic target against hepatocellular carcinoma.

13 July 2018

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Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

RecQ helicases: multifunctional genome caretakers

13 July 2018

1 reference

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

13 July 2018

1 reference

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IDH1 and IDH2 mutations in gliomas

13 July 2018

1 reference

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Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance

13 July 2018

1 reference

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An integrated genomic analysis of human glioblastoma multiforme

13 July 2018

1 reference

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Homologous recombination and maintenance of genome integrity: cancer and aging through the prism of human RecQ helicases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

RecQ helicases: guardian angels of the DNA replication fork

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Proautophagic drugs: a novel means to combat apoptosis-resistant cancers, with a special emphasis on glioblastomas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Human premature aging, DNA repair and RecQ helicases

13 July 2018

1 reference

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Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Clonogenic assay of cells in vitro.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

DNA repair helicases as targets for anti-cancer therapy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

DNA helicases required for homologous recombination and repair of damaged replication forks

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

DNA damage responses and their many interactions with the replication fork

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

The histone code at DNA breaks: a guide to repair?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

DNA helicases as targets for anti-cancer drugs.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis

13 July 2018

1 reference

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Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia.

13 July 2018

1 reference

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Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

13 July 2018

1 reference

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Junction of RecQ helicase biochemistry and human disease.

13 July 2018

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Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases

13 July 2018

1 reference

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Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide.

13 July 2018

1 reference

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Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein

13 July 2018

1 reference

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RecQ helicases: caretakers of the genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Differential regulation of human RecQ family helicases in cell transformation and cell cycle

13 July 2018

1 reference

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Rothmund-thomson syndrome responsible gene, RECQL4: genomic structure and products

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

Positional cloning of the Werner's syndrome gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

The Bloom's syndrome gene product is homologous to RecQ helicases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148559

The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells

13 July 2018

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Role for the Werner syndrome protein in the promotion of tumor cell growth.

21 January 2018

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Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

21 January 2018

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Proteomic studies on low- and high-grade human brain astrocytomas

21 January 2018

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The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities.

21 January 2018

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Mutation profiling of mismatch repair-deficient colorectal cncers using an in silico genome scan to identify coding microsatellites.

21 January 2018

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Involvement of the mismatch repair system in temozolomide-induced apoptosis

27 September 2018

1 reference

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A chronic myeloid leukemia-like syndrome case with del (12) (p12) in a Li-Fraumeni syndrome family

27 September 2018

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based on heuristic

Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers

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PubMed

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inferred from PubMed ID database lookup

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Identifiers

DOI

10.1186/1476-4598-10-83

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Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference