RecQ helicases: guardian angels of the DNA replication fork (Q33314341)

25 July 2017

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title

RecQ helicases: guardian angels of the DNA replication fork (English)

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25 July 2017

Csanád Z Bachrati

1

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PubMed ID

18188578

25 July 2017

Ian D Hickson

series ordinal

2

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25 July 2017

11 January 2008

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25 July 2017

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25 July 2017

117

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25 July 2017

3

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25 July 2017

219-233

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https://scigraph.springernature.com/pub.10.1007/s00412-007-0142-4

25 July 2017

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cites work

Bloom's syndrome protein response to ultraviolet-C radiation and hydroxyurea-mediated DNA synthesis inhibition

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RecQ helicases: suppressors of tumorigenesis and premature aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The Werner syndrome protein is involved in RNA polymerase II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Checking on DNA damage in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Deficient DNA repair in the human progeroid disorder, Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Biochemical characterization of the WRN-FEN-1 functional interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

A yeast gene required for DNA replication encodes a protein with homology to DNA helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Evidence for a replication function of FFA-1, the Xenopus orthologue of Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RecQ helicases: at the heart of genetic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

DNA damage-induced replication fork regression and processing in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Nascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The Bloom's syndrome gene product is homologous to RecQ helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Ultraviolet light sensitivity and delayed DNA-chain maturation in Bloom's syndrome fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RecJ exonuclease: substrates, products and interaction with SSB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Decrease in the average size of replicons in a Werner syndrome cell line by Simian virus 40 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

A retarded rate of DNA chain growth in Bloom's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The RecQ gene family in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Replisome assembly and the direct restart of stalled replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

A conserved G4 DNA binding domain in RecQ family helicases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Functional interaction between the Werner Syndrome protein and DNA polymerase delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Anticipating chromosomal replication fork arrest: SSB targets repair DNA helicases to active forks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The Werner and Bloom syndrome proteins catalyze regression of a model replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Rescue of stalled replication forks by RecG: simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

A unified view of the DNA-damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

RecFOR proteins load RecA protein onto gapped DNA to accelerate DNA strand exchange: a universal step of recombinational repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

A positive involvement of RecQL4 in UV-induced S-phase arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The Bloom's syndrome helicase can promote the regression of a model replication fork.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Asymmetry of DNA replication fork progression in Werner's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Characterisation of the interaction between WRN, the helicase/exonuclease defective in progeroid Werner's syndrome, and an essential replication factor, PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Stimulation of flap endonuclease-1 by the Bloom's syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

WRN helicase accelerates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Werner protein recruits DNA polymerase delta to the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Maintenance of fork integrity at damaged DNA and natural pause sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Role of the BLM helicase in replication fork management

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

DNA helicases required for homologous recombination and repair of damaged replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

FFA-1, a protein that promotes the formation of replication centers within nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Replication focus-forming activity 1 and the Werner syndrome gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Structure and function of mismatch repair proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Nuclear structure in normal and Bloom syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

Checkpoint-mediated control of replisome–fork association and signalling in response to replication pausing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00412-007-0142-4

An abnormal profile of DNA replication intermediates in Bloom's syndrome

21 January 2018

1 reference

12 December 2020

Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing

1 reference

12 December 2020

Role for BLM in replication-fork restart and suppression of origin firing after replicative stress

1 reference

12 December 2020

Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence

1 reference

12 December 2020

The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci

1 reference

12 December 2020

Autoradiographic studies of DNA replication in Werner's syndrome cells

1 reference

12 December 2020

RecO acts with RecF and RecR to protect and maintain replication forks blocked by UV-induced DNA damage in Escherichia coli

1 reference

12 December 2020

Abnormal fibroblast aging and DNA replication in the Werner syndrome

1 reference

12 December 2020

A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture

1 reference

12 December 2020

Transcriptional activation by the Werner syndrome gene product in yeast

1 reference

12 December 2020

Coupling of DNA Helicase and Endonuclease Activities of Yeast Dna2 Facilitates Okazaki Fragment Processing

1 reference

12 December 2020

RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli

1 reference

12 December 2020

Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts

1 reference

12 December 2020

Altered frequency of initiation sites of DNA replication in Werner's syndrome cells

1 reference

12 December 2020

Nuclear reconstitution in vitro: stages of assembly around protein-free DNA

1 reference

12 December 2020

10.1007/S00412-007-0142-4

Identifiers

DOI

1 reference

25 July 2017

1 reference

PubMed ID

18188578