Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies. (Q35203309)

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7 November 2019

review article

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title

Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies (English)

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7 November 2019

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4

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7 November 2019

author name string

Taro Fukao

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1

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7 November 2019

Yasuo Terauchi

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2

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7 November 2019

Takashi Kadowaki

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3

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7 November 2019

publication date

19 August 2003

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Journal of Molecular Medicine

7 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12928787%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

81

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7 November 2019

issue

9

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7 November 2019

page(s)

524-535

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https://scigraph.springernature.com/pub.10.1007/s00109-003-0475-2

7 November 2019

exact match

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cites work

Insulin activates the alpha isoform of class II phosphoinositide 3-kinase

1 reference

12 December 2020

Role of common cytokine receptor gamma chain (gamma(c))- and Jak3-dependent signaling in the proliferation and survival of murine mast cells

1 reference

12 December 2020

Differential responsiveness of purified mouse c-kit+ mast cells and their progenitors to IL-3 and stem cell factor.

1 reference

12 December 2020

p110δ, a novel phosphoinositide 3-kinase in leukocytes

1 reference

12 December 2020

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

12 December 2020

Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.

1 reference

12 December 2020

Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways

1 reference

12 December 2020

The role of PI3K in immune cells

1 reference

12 December 2020

Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity

1 reference

12 December 2020

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

12 December 2020

Intestinal mast cell response and mucosal defence against Strongyloides venezuelensis in interleukin-3-hyporesponsive mice

1 reference

12 December 2020

syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction

1 reference

12 December 2020

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

12 December 2020

Intraepithelial infiltration by mast cells with both connective tissue-type and mucosal-type characteristics in gut, trachea, and kidneys of IL-9 transgenic mice.

1 reference

12 December 2020

Selective effector mechanisms for the expulsion of intestinal helminths

1 reference

12 December 2020

Interleukin 10: a novel stimulatory factor for mast cells and their progenitors

1 reference

12 December 2020

A novel class II phosphoinositide 3-kinase predominantly expressed in the liver and its enhanced expression during liver regeneration

1 reference

12 December 2020

Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo

1 reference

12 December 2020

Mast cells as sentinels of innate immunity

1 reference

12 December 2020

1 reference

12 December 2020

Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.

1 reference

12 December 2020

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

1 reference

12 December 2020

Identification of a committed precursor for the mast cell lineage.

1 reference

12 December 2020

IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

1 reference

12 December 2020

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

1 reference

12 December 2020

Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses

1 reference

12 December 2020

Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases

1 reference

12 December 2020

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation

1 reference

12 December 2020

The role of Th2 cytokines in mast cell homeostasis

1 reference

12 December 2020

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1 reference

12 December 2020

Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation

1 reference

12 December 2020

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1 reference

12 December 2020

PI3K in lymphocyte development, differentiation and activation

1 reference

12 December 2020

The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking

1 reference

12 December 2020

Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors

1 reference

12 December 2020

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

1 reference

12 December 2020

Mast cell and basophil development

1 reference

12 December 2020

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

1 reference

12 December 2020

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

12 December 2020

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

12 December 2020

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

1 reference

12 December 2020

The kit ligand, stem cell factor

1 reference

12 December 2020

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

1 reference

12 December 2020

Vav1 regulates phospholipase cgamma activation and calcium responses in mast cells.

1 reference

12 December 2020

Role of tyrosine kinases in lymphocyte activation

1 reference

12 December 2020

LAT is essential for Fc(epsilon)RI-mediated mast cell activation

1 reference

12 December 2020

Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.

1 reference

12 December 2020

New concepts about the mast cell

1 reference

12 December 2020

Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites

1 reference

12 December 2020

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

12 December 2020

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

1 reference

12 December 2020

Lymphocyte signalling: a coordinating role for Vav?

1 reference

12 December 2020

Phosphoinositide kinases

1 reference

12 December 2020

1 reference

12 December 2020

The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology

1 reference

12 December 2020

Structure and function of the chemical mediators of mast cells

1 reference

12 December 2020

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

1 reference

12 December 2020

IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions

1 reference

12 December 2020

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

1 reference

12 December 2020

The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

1 reference

12 December 2020

The alpha-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs

1 reference

12 December 2020

Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles

1 reference

12 December 2020

The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles

1 reference

12 December 2020

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

1 reference

12 December 2020

Activation of protein tyrosine kinase p72syk by Fc epsilon RI aggregation in rat basophilic leukemia cells. p72syk is a minor component but the major protein tyrosine kinase of pp72.

1 reference

12 December 2020

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system

1 reference

12 December 2020

Structural insights into phosphoinositide 3-kinase catalysis and signalling

1 reference

12 December 2020

Critical protective role of mast cells in a model of acute septic peritonitis

1 reference

12 December 2020

Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation

1 reference

12 December 2020

A perspective: regulation of IgE receptor-mediated mast cell responses by a LAT-organized plasma membrane-localized signaling complex

1 reference

12 December 2020

Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

1 reference

12 December 2020

Requirement of Gab2 for mast cell development and KitL/c-Kit signaling

1 reference

12 December 2020

Cytokine-mediated regulation of chronic intestinal helminth infection

1 reference

12 December 2020

Mast cells as a source of multifunctional cytokines

1 reference

12 December 2020

Murine granulocyte-macrophage and mast cell colony formation promoted by nerve growth factor

1 reference

12 December 2020

A redox-triggered ras-effector interaction. Recruitment of phosphatidylinositol 3'-kinase to Ras by redox stress.

1 reference

12 December 2020

Allergy, parasites, and the hygiene hypothesis

1 reference

12 December 2020

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

1 reference

12 December 2020

The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines

1 reference

12 December 2020

Kinetic study of mast-cell growth factor production by lymphocytes during the course of Strongyloides ratti infection in mice

1 reference

12 December 2020

SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells

1 reference

12 December 2020

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

12 December 2020

Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites

1 reference

12 December 2020

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

12 December 2020

Phosphoinositide kinases

1 reference

12 December 2020

New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)

1 reference

12 December 2020

cDNA cloning of a third human C2-domain-containing class II phosphoinositide 3-kinase, PI3K-C2gamma, and chromosomal assignment of this gene (PIK3C2G) to 12p12

1 reference

12 December 2020

Dendritic cells and the control of immunity

1 reference

12 December 2020

Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene

1 reference

12 December 2020

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

1 reference

12 December 2020

Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells

1 reference

12 December 2020

The diverse roles of mast cells

1 reference

12 December 2020

The phosphatidylinositol 3-kinase inhibitor wortmannin blocks mast cell exocytosis but not IL-6 production

1 reference

12 December 2020

A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole

1 reference

12 December 2020

Mast cells and basophils

1 reference

12 December 2020

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

1 reference

12 December 2020

Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation

1 reference

12 December 2020

Critical role for signal transducer and activator of transcription factor 6 in mediating intestinal muscle hypercontractility and worm expulsion in Trichinella spiralis-infected mice

1 reference

12 December 2020

Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma

1 reference

12 December 2020

A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction

1 reference

12 December 2020

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

12 December 2020

Role of phosphatidylinositol 3-kinase in degranulation induced by IgE-dependent and -independent mechanisms in rat basophilic RBL-2H3 (ml) cells

1 reference

12 December 2020

Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex

1 reference

12 December 2020

Distinct Mechanisms of α5β1Integrin Activation by Ha-Ras and R-Ras

1 reference

12 December 2020

Essential role for Gab2 in the allergic response

1 reference

12 December 2020

Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits

1 reference

12 December 2020

Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors

1 reference

12 December 2020

Regulation of mast-cell and basophil function and survival by IgE.

1 reference

12 December 2020

Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase

1 reference

12 December 2020

10.1007/S00109-003-0475-2

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12928787%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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