Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy (Q35210714)

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English	Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy	scientific article

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scholarly article

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5 December 2019

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy (English)

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5 December 2019

congenital disorder

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1 reference

based on heuristic

inferred from title

congenital generalized lipodystrophy

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

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inferred from title

4

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5 December 2019

author name string

I Shimomura

1

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5 December 2019

R E Hammer

2

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5 December 2019

J A Richardson

3

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5 December 2019

Y Bashmakov

5

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J L Goldstein

6

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M S Brown

7

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publication date

1 October 1998

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5 December 2019

Genes & Development

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12

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3182-3194

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20

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5 December 2019

Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

1 reference

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28 July 2018

Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand

1 reference

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28 July 2018

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Troglitazone action is independent of adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

1 reference

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28 July 2018

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

1 reference

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28 July 2018

Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene.

1 reference

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28 July 2018

Adipogenesis and obesity: rounding out the big picture

1 reference

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28 July 2018

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Generalized lipodystrophy, congenital and acquired (lipoatrophy).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism

1 reference

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28 July 2018

Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation

1 reference

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28 July 2018

Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes

1 reference

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28 July 2018

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

1 reference

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28 July 2018

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

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28 July 2018

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

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28 July 2018

SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317215

28 July 2018

The complete nucleotide sequence of the rat 18S ribosomal RNA gene and comparison with the respective yeast and frog genes

1 reference

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28 July 2018

The mitochondrial uncoupling protein gene. Correlation of exon structure to transmembrane domains

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28 July 2018

From dietary glucose to liver glycogen: the full circle round

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28 July 2018

Adipsin, the adipocyte serine protease: gene structure and control of expression by tumor necrosis factor

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28 July 2018

Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit.

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28 July 2018

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

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28 July 2018

A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo

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28 July 2018

Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors

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28 July 2018

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells

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28 July 2018

Peculiar distribution of adipose tissue in patients with congenital generalized lipodystrophy

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28 July 2018

Lipodystrophy and gigantism with associated endocrine manifestations. A new diencephalic syndrome?

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26 September 2018

A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

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26 September 2018

Indinavir-associated lipodystrophy.

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26 September 2018

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

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26 September 2018

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26 September 2018

Cloning of the mouse insulin receptor substrate-1 (IRS-1) gene and complete sequence of mouse IRS-1.

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26 September 2018

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26 September 2018

Characterization of insulin resistance and NIDDM in transgenic mice with reduced brown fat.

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26 September 2018

Suitability of 2-deoxyglucose for in vitro measurement of glucose transport activity in skeletal muscle

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12 December 2020

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The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9784493

12 December 2020

based on heuristic

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Cellular and vascular development in immature rat adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/9784493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine structural studies on white adipocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9784493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9784493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1101/GAD.12.20.3182

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5 December 2019

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5 December 2019

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5 December 2019

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