JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth. (Q35214530)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25810010%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25810010%20AND%20SRC:MED&resulttype=core&format=json

head and neck squamous cell carcinoma

3 March 2020

main subject

1 reference

5

1 reference

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3 March 2020

Vivian Lui

8

1 reference

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3 March 2020

Simion Chiosea

10

1 reference

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3 March 2020

Jennifer Rubin Grandis

11

object named as

Jennifer R Grandis

1 reference

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3 March 2020

1

Malabika Sen

1 reference

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3 March 2020

2

Netanya I Pollock

1 reference

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3 March 2020

4

Kara A DeGrave

1 reference

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3 March 2020

7

Sonali Joyce

1 reference

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3 March 2020

author name string

John Black

3

1 reference

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3 March 2020

Maria L Freilino

6

1 reference

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3 March 2020

Yan Zeng

9

1 reference

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3 March 2020

publication date

1 March 2015

1 reference

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3 March 2020

1 reference

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3 March 2020

volume

17

1 reference

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3 March 2020

issue

3

1 reference

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3 March 2020

page(s)

256-264

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The Janus kinases inhibitor AZD1480 attenuates growth of small cell lung cancers in vitro and in vivo

3 March 2020

cites work

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Nucleic acid-based approaches to STAT inhibition

13 July 2018

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Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer

13 July 2018

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Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

13 July 2018

1 reference

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Comprehensive review of JAK inhibitors in myeloproliferative neoplasms.

13 July 2018

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A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins

13 July 2018

1 reference

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Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo

13 July 2018

1 reference

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Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts

13 July 2018

1 reference

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AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines

13 July 2018

1 reference

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The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma.

13 July 2018

1 reference

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First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

13 July 2018

1 reference

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Genome-wide integrative analysis revealed a correlation between lengths of copy number segments and corresponding gene expression profile

13 July 2018

1 reference

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Targeting the interleukin-6/Jak/stat pathway in human malignancies

13 July 2018

1 reference

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Therapeutic potential of AZD1480 for the treatment of human glioblastoma

13 July 2018

1 reference

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Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analog

13 July 2018

1 reference

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Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies

13 July 2018

1 reference

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STAT3 signaling: anticancer strategies and challenges.

13 July 2018

1 reference

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The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival

13 July 2018

1 reference

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Integrative analysis of DNA copy number and gene expression in metastatic oral squamous cell carcinoma identifies genes associated with poor survival

13 July 2018

1 reference

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Defining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: implications for future therapeutic approaches

13 July 2018

1 reference

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Therapeutic suppression of constitutive and inducible JAK\STAT activation in head and neck squamous cell carcinoma.

13 July 2018

1 reference

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The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors

13 July 2018

1 reference

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Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells.

13 July 2018

1 reference

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Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

13 July 2018

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Intratumoral epidermal growth factor receptor antisense DNA therapy in head and neck cancer: first human application and potential antitumor mechanisms

13 July 2018

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Constitutive activation of signal transducer and activator of transcription 5 contributes to tumor growth, epithelial-mesenchymal transition, and resistance to epidermal growth factor receptor targeting

13 July 2018

1 reference

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STAT3 as a therapeutic target in head and neck cancer

13 July 2018

1 reference

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The JAK2V617F tyrosine kinase mutation in myeloproliferative disorders: status report and immediate implications for disease classification and diagnosis

13 July 2018

1 reference

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The JAK/STAT signaling pathway

13 July 2018

1 reference

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The STATs of cancer--new molecular targets come of age

13 July 2018

1 reference

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Regulation of JAK-STAT signalling in the immune system

13 July 2018

1 reference

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JAK/STAT signaling pathways and cancer. Janus kinases/signal transducers and activators of transcription.

13 July 2018

1 reference

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Pharmaceutical intervention in the JAK/STAT signaling pathway

13 July 2018

1 reference

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Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers

13 July 2018

1 reference

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Targeting STAT3 in cancer: how successful are we?

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25810010

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEO.2015.01.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25810010%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25810010%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

25810010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25810010%20AND%20SRC:MED&resulttype=core&format=json