Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics (Q35228718)

7 August 2017

1 reference

title

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics (English)

1 reference

7 August 2017

Artak Tovmasyan

3

0 references

Xiaodong Ye

Xiaodong Ye

5

0 references

Julio S Reboucas

Julio S Reboucas

4

0 references

Ludmil T. Benov

Ludmil Benov

9

0 references

Kam W. Leong

Kam W Leong

6

0 references

Ines Batinic-Haberle

1

Ines Batinic-Haberle

1 reference

7 August 2017

8

Zeljko Vujaskovic

1 reference

7 August 2017

Zrinka Rajic

2

1 reference

PubMed ID

21616142

7 August 2017

Mark W Dewhirst

7

1 reference

PubMed ID

21616142

7 August 2017

Ivan Spasojevic

10

1 reference

7 August 2017

6 May 2011

1 reference

Free Radical Biology and Medicine

7 August 2017

1 reference

7 August 2017

51

1 reference

7 August 2017

5

1 reference

7 August 2017

1035-1053

1 reference

Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.

13 July 2018

1 reference

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1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria.

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

13 July 2018

1 reference

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Redox modulation protects islets from transplant-related injury

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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A metalloporphyrin antioxidant alters cytokine responses after irradiation in a prostate tumor model

13 July 2018

1 reference

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Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli

13 July 2018

1 reference

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The in vitro effects of superoxide, some commercially available antioxidants and red palm oil on sperm motility.

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.

13 July 2018

1 reference

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13 July 2018

1 reference

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Reactive oxygen species-dependent signaling regulates cancer

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Increased manganese superoxide dismutase expression or treatment with manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.

13 July 2018

1 reference

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Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways

13 July 2018

1 reference

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13 July 2018

1 reference

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Oxidative inactivation of key mitochondrial proteins leads to dysfunction and injury in hepatic ischemia reperfusion

13 July 2018

1 reference

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13 July 2018

1 reference

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Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.

13 July 2018

1 reference

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Targeting lipophilic cations to mitochondria.

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection

13 July 2018

1 reference

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Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion.

13 July 2018

1 reference

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Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria

13 July 2018

1 reference

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Lost in translation: treatment trials in the SOD1 mouse and in human ALS.

13 July 2018

1 reference

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Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury

13 July 2018

1 reference

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Catalytic antioxidants to treat amyotropic lateral sclerosis

13 July 2018

1 reference

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Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

13 July 2018

1 reference

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Regulation of novel superoxide-producing NAD(P)H oxidases

13 July 2018

1 reference

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13 July 2018

1 reference

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A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.

13 July 2018

1 reference

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Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules

13 July 2018

1 reference

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Tumor suppressive effects of MnSOD overexpression may involve imbalance in peroxide generation versus peroxide removal

13 July 2018

1 reference

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Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion

13 July 2018

1 reference

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Macrophage signaling and respiratory burst

13 July 2018

1 reference

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Rotational isomers of N-alkylpyridylporphyrins and their metal complexes. HPLC separation, (1)H NMR and X-ray structural characterization, electrochemistry, and catalysis of O(2)(.-) disproportionation

13 July 2018

1 reference

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A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone

13 July 2018

1 reference

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Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease

13 July 2018

1 reference

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H2O2-induced cell death in human glioma cells: role of lipid peroxidation and PARP activation

13 July 2018

1 reference

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13 July 2018

1 reference

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13 July 2018

1 reference

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Catalysis of the disproportionation of superoxide by metalloporphyrins

13 July 2018

1 reference

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Metalloporphyrin synergizes with ascorbic acid to inhibit cancer cell growth through fenton chemistry

13 July 2018

1 reference

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Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Time-dependant protective effects of mangenese(III) tetrakis (1-methyl-4-pyridyl) porphyrin on mitochondrial function following renal ischemia-reperfusion injury

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Neuroprotection against staurosporine by metalloporphyrins independent of antioxidant capability

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Effects of genistein following fractionated lung irradiation in mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Effect of a metalloporphyrin antioxidant (MnTE-2-PyP) on the response of a mouse prostate cancer model to radiation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Radioprotective effect of a metalloporphyrin compound in rat eye model.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Pure manganese(III) 5,10,15,20-tetrakis(4-benzoic acid)porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure-activity relationship as a watchdog mechanism in experimental therapeutics and biology

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Decreased hepatic ischemia-reperfusion injury by manganese-porphyrin complexes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Manganese porphyrin given at symptom onset markedly extends survival of ALS mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Osmium tetroxide, used in the treatment of arthritic joints, is a fast mimic of superoxide dismutase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

A mechanism-based antioxidant approach for the reduction of skin carcinogenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Mouse spinal cord compression injury is ameliorated by intrathecal cationic manganese(III) porphyrin catalytic antioxidant therapy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Complementation of SOD-deficient Escherichia coli by manganese porphyrin mimics of superoxide dismutase activity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Tetrahydrobiopterin rapidly reduces the SOD mimic Mn(III) ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

A manganese porphyrin complex is a novel radiation protector

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: implication for their use in targeting oxidation-reduction reactions in innate immunity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Preischemic and Postischemic Administration of AEOL10113 Reduces Infarct Size in a Rat Model of Myocardial Ischemia and Reperfusion

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

A catalytic antioxidant attenuates alveolar structural remodeling in bronchopulmonary dysplasia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Inhibition of airway inflammation and hyperreactivity by an antioxidant mimetic

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178885

26 September 2018

1 reference

12 December 2020

Response of human islets to isolation stress and the effect of antioxidant treatment

1 reference

12 December 2020

Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria

1 reference

12 December 2020

Defective superoxide production by granulocytes from patients with chronic granulomatous disease

1 reference

12 December 2020

Catalysis of the disproportionation of superoxide by metalloporphyrins. III

1 reference

12 December 2020

Chemical Properties of Water-soluble Porphyrins 3. The Reaction of Superoxide Radicals with Some Metalloporphyrins

1 reference

12 December 2020

Chemical properties of water-soluble porphyrins. 4. The reaction of a 'picket-fence-like' iron (III) complex with the superoxide oxygen couple

1 reference

12 December 2020

Chemical properties of water-soluble porphyrins. 5. Reactions of some manganese (III) porphyrins with the superoxide and other reducing radicals

1 reference

12 December 2020

Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo

1 reference

12 December 2020

The mechanism of the auxotrophy for sulfur-containing amino acids imposed upon Escherichia coli by superoxide

1 reference

12 December 2020

A potent superoxide dismutase mimic: manganese beta-octabromo-meso-tetrakis-(N-methylpyridinium-4-yl) porphyrin

1 reference

12 December 2020

Superoxide imposes leakage of sulfite from Escherichia coli

1 reference

12 December 2020

The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic

1 reference

12 December 2020

Why superoxide imposes an aromatic amino acid auxotrophy on Escherichia coli. The transketolase connection

1 reference

12 December 2020

Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite

1 reference

12 December 2020

Kinetic properties of Cu,Zn-superoxide dismutase as a function of metal content--order restored

1 reference

12 December 2020

New approach to the activation of anti-cancer pro-drugs by metalloporphyrin-based cytochrome P450 mimics in all-aqueous biologically relevant system

1 reference

12 December 2020

Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles

1 reference

12 December 2020

Protection from radiation-induced pneumonitis using cerium oxide nanoparticles

1 reference

12 December 2020

Survival or death: the redox paradox

1 reference

12 December 2020

Superoxide dismutases: anti- versus pro- oxidants?

1 reference

12 December 2020

10.1016/J.FREERADBIOMED.2011.04.046

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

21616142