A PKM2 signature in the failing heart. (Q35235782)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25735978%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

A PKM2 signature in the failing heart (English)

1 reference

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2 March 2020

4

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2 March 2020

author name string

Meredith L Rees

1

1 reference

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2 March 2020

Janani Subramaniam

2

1 reference

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2 March 2020

Yuanteng Li

3

1 reference

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2 March 2020

O Howard Frazier

5

1 reference

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2 March 2020

Heinrich Taegtmeyer

6

1 reference

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2 March 2020

language of work or name

English

0 references

publication date

28 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25735978%20AND%20SRC:MED&resulttype=core&format=json

Biochemical and Biophysical Research Communications

2 March 2020

published in

1 reference

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2 March 2020

volume

459

1 reference

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2 March 2020

issue

3

1 reference

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2 March 2020

page(s)

430-436

1 reference

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Heart failure in remission for more than 13 years after removal of a left ventricular assist device

2 March 2020

cites work

1 reference

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Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function

13 July 2018

1 reference

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Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy.

13 July 2018

1 reference

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Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity

13 July 2018

1 reference

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PKM2, a Central Point of Regulation in Cancer Metabolism

13 July 2018

1 reference

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

13 July 2018

1 reference

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

13 July 2018

1 reference

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Molecular mechanisms of hypertension and heart failure due to antiangiogenic cancer therapies

13 July 2018

1 reference

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Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Return to the fetal gene program: a suggested metabolic link to gene expression in the heart

13 July 2018

1 reference

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The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Understanding the Warburg effect: the metabolic requirements of cell proliferation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib

13 July 2018

1 reference

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Therapy insight: Management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Return to the fetal gene program protects the stressed heart: a strong hypothesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Myocardial substrate metabolism in the normal and failing heart

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

On respiratory impairment in cancer cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Cellular oncogenes in cardiovascular disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

A hemodynamic load in vivo induces cardiac expression of the cellular oncogene, c-myc

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Remission of diabetes while on sunitinib treatment for renal cell carcinoma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Mechanical unloading of the failing human heart fails to activate the protein kinase B/Akt/glycogen synthase kinase-3beta survival pathway.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Metabolic gene expression in fetal and failing human heart

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380635

Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25735978

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Isolation and culture of adult mouse cardiac myocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25735978

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBRC.2015.02.122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25735978%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25735978%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

25735978

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25735978%20AND%20SRC:MED&resulttype=core&format=json