Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia (Q35272389)

7 August 2017

title

Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia (English)

1 reference

7 August 2017

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D G Walker

1

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7 August 2017

A M Whetzel

series ordinal

2

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7 August 2017

L-F Lue

series ordinal

3

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7 August 2017

language of work or name

English

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publication date

5 October 2014

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7 August 2017

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7 August 2017

volume

302

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7 August 2017

page(s)

121-137

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Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model.

7 August 2017

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27 July 2018

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Regulation of Janus kinases by SOCS proteins

27 July 2018

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socs7, a target gene of microRNA-145, regulates interferon-β induction through STAT3 nuclear translocation in bladder cancer cells

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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SOCS3 deficiency promotes M1 macrophage polarization and inflammation.

27 July 2018

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Beyond amyloid: the future of therapeutics for Alzheimer's disease

27 July 2018

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Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

27 July 2018

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High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes

27 July 2018

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Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation.

27 July 2018

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Evaluation of a previously suggested plasma biomarker panel to identify Alzheimer's disease

27 July 2018

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Striatal amyloid plaque density predicts Braak neurofibrillary stage and clinicopathological Alzheimer's disease: implications for amyloid imaging

27 July 2018

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Both type I and II IFN induce insulin resistance by inducing different isoforms of SOCS expression in 3T3-L1 adipocytes

27 July 2018

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Does a pro-inflammatory process precede Alzheimer's disease and mild cognitive impairment?

27 July 2018

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Inflammatory risk factors and pathologies associated with Alzheimer's disease

27 July 2018

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Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3.

27 July 2018

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Assessing activation states in microglia

27 July 2018

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Microglia activation and anti-inflammatory regulation in Alzheimer's disease

27 July 2018

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High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells

27 July 2018

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CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.

27 July 2018

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SOCS1 and SOCS3 in the control of CNS immunity

27 July 2018

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Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease

27 July 2018

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27 July 2018

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Putting out the fire: coordinated suppression of the innate and adaptive immune systems by SOCS1 and SOCS3 proteins

27 July 2018

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Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes

27 July 2018

1 reference

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Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins

27 July 2018

1 reference

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Cytokine signaling modules in inflammatory responses

27 July 2018

1 reference

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Structure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR Degradation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

27 July 2018

1 reference

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Molecular mechanism of lipopolysaccharide-induced SOCS-3 gene expression in macrophages and microglia.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-alpha involves activation of the MKK6/p38MAPK/MK2 cascade

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination

27 July 2018

1 reference

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The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia

27 July 2018

1 reference

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Gene expression changes by amyloid beta peptide-stimulated human postmortem brain microglia identify activation of multiple inflammatory processes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

27 July 2018

1 reference

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Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing

27 July 2018

1 reference

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JAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation

27 July 2018

1 reference

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Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells

27 July 2018

1 reference

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Differential expression of suppressors of cytokine signaling-1, -2, and -3 in the rat hippocampus after seizure: implications for neuromodulation by gp130 cytokines

27 July 2018

1 reference

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Cytokine signaling in the brain: putting a SOCS in it?

27 July 2018

1 reference

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Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis

27 July 2018

1 reference

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Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia.

27 July 2018

1 reference

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Diagnostic criteria for Parkinson disease

27 July 2018

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Transforming growth factor-alpha (TGF-alpha) and epidermal growth factor-receptor (EGF-R) immunoreactivity in normal and pathologic brain.

27 July 2018

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Epidermal growth factor receptor expression in demented and aged human brain

27 July 2018

1 reference

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Quantitative analysis of the suppressors of cytokine signaling 1 and 3 in peripheral blood leukocytes of patients with multiple sclerosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Downregulation of microRNA-431 by human interferon-β inhibits viability of medulloblastoma and glioblastoma cells via upregulation of SOCS6.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Neuroinflammatory phenotypes and their roles in Alzheimer's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

SOCS proteins in development and disease

26 September 2018

1 reference

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Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson's-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses.

26 September 2018

1 reference

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The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.

26 September 2018

1 reference

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Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

26 September 2018

1 reference

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Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

26 September 2018

1 reference

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Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging

26 September 2018

1 reference

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Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease

26 September 2018

1 reference

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Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition

26 September 2018

1 reference

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Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells.

26 September 2018

1 reference

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Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Enhanced expression of SOCS-2 in the rat hippocampus after transient forebrain ischemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

PMA activates Stat3 in the Jak/Stat pathway and induces SOCS5 in rat brain astrocytes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Statins induce suppressor of cytokine signaling-3 in macrophages

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Expression of "suppressor of cytokine signalling" (SOCS) genes in the developing and adult mouse nervous system.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Application of the National Institute on Aging (NIA)-Reagan Institute criteria for the neuropathological diagnosis of Alzheimer disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting multiple sclerosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385752

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

15 November 2018

1 reference

12 December 2020

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

1 reference

12 December 2020

The effect of disease activity on leptin, leptin receptor and suppressor of cytokine signalling-3 expression in relapsing-remitting multiple sclerosis

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12 December 2020

CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover

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12 December 2020

Modulation of signal transducers and activators of transcription (STAT) factor pathways during focal cerebral ischaemia: a gene expression array study in rat hippocampus after middle cerebral artery occlusion

1 reference

12 December 2020

10.1016/J.NEUROSCIENCE.2014.09.052

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference