The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells (Q35535619)

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scientific article published on 23 July 2011

Language	Label	Description	Also known as
English	The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells	scientific article published on 23 July 2011

Statements

scholarly article

1 reference

Europe PubMed Central

8 August 2017

The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells (English)

1 reference

Europe PubMed Central

8 August 2017

negative regulation of cholesterol esterification

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

ATP binding cassette subfamily A member 2

1 reference

GOA release 2020-03-11

regulation of cholesterol biosynthetic process

1 reference

GOA release 2020-03-11

ATP-binding cassette sub-family A member 2

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

author name string

Warren Davis

1

1 reference

Europe PubMed Central

8 August 2017

language of work or name

0 references

publication date

23 July 2011

1 reference

Europe PubMed Central

8 August 2017

Biochimica et Biophysica Acta

1 reference

Europe PubMed Central

8 August 2017

1811

1 reference

Europe PubMed Central

8 August 2017

12

1 reference

Europe PubMed Central

8 August 2017

1152-1164

1 reference

Europe PubMed Central

8 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3210877/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

APOE and cholesterol homeostasis in Alzheimer's disease

1 reference

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The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Aβ fragment generation

1 reference

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12 July 2018

PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain

1 reference

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Formation and function of apolipoprotein E-containing lipoproteins in the nervous system

1 reference

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Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease

1 reference

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Lipid rafts as a membrane-organizing principle

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Transport of lipids by ABC proteins: interactions and implications for cellular toxicity, viability and function

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Sterols in the central nervous system

1 reference

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Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease

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No association of DAPK1 and ABCA2 SNPs on chromosome 9 with Alzheimer's disease

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The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2

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Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

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ABCA2 deficiency results in abnormal sphingolipid metabolism in mouse brain.

1 reference

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The proprotein convertases and their implication in sterol and/or lipid metabolism

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Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes

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ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease

1 reference

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Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

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Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells

1 reference

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Association of ABCA2 expression with determinants of Alzheimer's disease

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

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Importance of different pathways of cellular cholesterol efflux

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The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

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Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2)

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Uptake of lipoproteins for axonal growth of sympathetic neurons

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Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol

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Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.

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Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member.

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Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene.

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Beyond LDL cholesterol, a new role for PCSK9.

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Expression of ABCA2 protein in both non-myelin-forming and myelin-forming Schwann cells in the rodent peripheral nerve.

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Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells.

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Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol

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ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination

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1 reference

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1 reference

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Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer's disease

1 reference

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Identifiers

10.1016/J.BBALIP.2011.07.010

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

ResearchGate publication ID

0 references

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