STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells (Q35644477)

9 August 2017

title

STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells (English)

1 reference

9 August 2017

1 reference

Guanjun Dong

1

1 reference

9 August 2017

Ming You

2

1 reference

9 August 2017

Liang Ding

3

1 reference

9 August 2017

Hongye Fan

4

1 reference

9 August 2017

Fei Liu

5

1 reference

9 August 2017

Deshan Ren

6

1 reference

9 August 2017

Yayi Hou

7

1 reference

9 August 2017

publication date

7 May 2015

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9 August 2017

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9 August 2017

volume

38

1 reference

9 August 2017

issue

5

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9 August 2017

page(s)

441-451

1 reference

Suppression of systemic autoimmunity by the innate immune adaptor STING.

9 August 2017

cites work

1 reference

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Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice

27 July 2018

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A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1

27 July 2018

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Inflammation-driven carcinogenesis is mediated through STING

27 July 2018

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Intrinsic self-DNA triggers inflammatory disease dependent on STING.

27 July 2018

1 reference

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Activation of the STING adaptor attenuates experimental autoimmune encephalitis.

27 July 2018

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SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature

27 July 2018

1 reference

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27 July 2018

Immune sensing of DNA

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Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

27 July 2018

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STING and the innate immune response to nucleic acids in the cytosol

27 July 2018

1 reference

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The broad-spectrum antiviral functions of IFIT and IFITM proteins

27 July 2018

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STING manifests self DNA-dependent inflammatory disease

27 July 2018

1 reference

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Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

27 July 2018

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Viperin, MTAP44, and protein kinase R contribute to the interferon-induced inhibition of Bunyamwera Orthobunyavirus replication

27 July 2018

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Environmental triggers and epigenetic deregulation in autoimmune disease

27 July 2018

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Structural modification of DNA--a therapeutic option in SLE?

27 July 2018

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Activation of STAT6 by STING is critical for antiviral innate immunity

27 July 2018

1 reference

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Interferon-α induces unabated production of short-lived plasma cells in pre-autoimmune lupus-prone (NZB×NZW)F1 mice but not in BALB/c mice

27 July 2018

1 reference

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Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

27 July 2018

1 reference

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Nucleic acid recognition by the innate immune system

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

The ISG56/IFIT1 gene family

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

STAT1 activation regulates proliferation and differentiation of renal progenitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response

27 July 2018

1 reference

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The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

27 July 2018

1 reference

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Infections and autoimmunity: the multifaceted relationship

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

27 July 2018

1 reference

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The effect of melanism and vitamin D synthesis on the incidence of autoimmune disease

27 July 2018

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Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alpha

27 July 2018

1 reference

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

27 July 2018

1 reference

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Type I interferon in systemic lupus erythematosus.

27 July 2018

1 reference

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Interferon, Mx, and viral countermeasures

27 July 2018

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

27 July 2018

1 reference

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Mechanisms of disease: Environmental factors in the pathogenesis of rheumatic disease

27 July 2018

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

27 July 2018

1 reference

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Environment and systemic lupus erythematosus: an overview

27 July 2018

1 reference

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RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

27 July 2018

1 reference

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Mechanisms of type-I- and type-II-interferon-mediated signalling

27 July 2018

1 reference

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Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells

27 July 2018

1 reference

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

27 July 2018

1 reference

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Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

27 July 2018

1 reference

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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

27 July 2018

1 reference

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Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

27 July 2018

1 reference

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Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

27 July 2018

1 reference

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Gene structure and function of the 2'-5'-oligoadenylate synthetase family.

27 July 2018

1 reference

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Epidermal growth factor-induced growth inhibition requires Stat1 activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

STATs and gene regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

27 July 2018

1 reference

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A protein tyrosine kinase in the interferon alpha/beta signaling pathway

27 July 2018

1 reference

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Systemic lupus erythematosus.

27 July 2018

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Cytomegalovirus as a Trigger for Systemic Lupus Erythematosus

25 September 2018

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

25 September 2018

1 reference

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

25 September 2018

1 reference

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25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Anti-apoptotic signals of granulocyte-macrophage colony-stimulating factor are transduced via Jak2 tyrosine kinase in eosinophils.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443286

Severe herpesvirus infections in an adolescent without natural killer cells

25 September 2018

1 reference

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25 September 2018

DNA drives autoimmunity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25947293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Drug-induced autoimmunity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25947293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25947293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.14348/MOLCELLS.2015.2359

1 reference

9 August 2017

1 reference

9 August 2017

1 reference