Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans (Q35696531)

9 August 2017

Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans (English)

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9 August 2017

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4

C Ronald Kahn

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9 August 2017

Florencia Halperin

1

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9 August 2017

Ximena Lopez

2

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9 August 2017

Raquel Manning

3

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9 August 2017

Rohit N Kulkarni

5

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9 August 2017

Allison B Goldfine

6

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9 August 2017

language of work or name

English

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publication date

1 February 2012

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9 August 2017

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9 August 2017

61

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9 August 2017

301-309

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9 August 2017

2

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

9 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Exogenous insulin enhances glucose-stimulated insulin response in healthy humans independent of changes in free fatty acids

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β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition

12 July 2018

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Insulin infusion during normoglycemia modulates insulin secretion according to whole-body insulin sensitivity

12 July 2018

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Diagnosis and classification of diabetes mellitus

12 July 2018

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Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms

12 July 2018

1 reference

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Insulin reciprocally regulates glucagon secretion in humans

12 July 2018

1 reference

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Insulin enhances glucose-stimulated insulin secretion in healthy humans

12 July 2018

1 reference

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Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.

12 July 2018

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Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons

12 July 2018

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Insulin signaling in alpha cells modulates glucagon secretion in vivo

12 July 2018

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Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

12 July 2018

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Growth factor control of pancreatic islet regeneration and function

12 July 2018

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Acute effects of insulin on beta-cells from transplantable human islets

12 July 2018

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Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

12 July 2018

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Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN β‐cell line and human islets of Langerhans

12 July 2018

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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

12 July 2018

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

12 July 2018

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High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program

12 July 2018

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Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

12 July 2018

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Insulin-stimulated insulin secretion in single pancreatic beta cells.

12 July 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

12 July 2018

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Novel, non-crinophagic, degradation of connecting peptide in transformed pancreatic beta cells

12 July 2018

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Prevention of the Glucose Intolerance of Thiazide Diuretics by Maintenance of Body Potassium

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Effect of exogenous bonito insulin on endogenous insulin secretion in dogs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Further support for inhibition of endogenous insulin secretion by exogenous insulin.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Monomeric insulins and their experimental and clinical implications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Effects of arterial versus venous sampling on analysis of glucose kinetics in man.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Failure of Exogenous Insulin to Inhibit Insulin Secretion in Man

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Glucose clamp technique: a method for quantifying insulin secretion and resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Studies on the question of a possible autoregulation of insulin secretion (author's transl)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Identification of insulin signaling elements in human beta-cells: autocrine regulation of insulin gene expression.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Antegrade intravenous catheterization for metabolic studies in man.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Glucose-dependent promotion of insulin release from mouse pancreatic islets by the insulin-mimetic compound L-783,281.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Feedback inhibition of insulin secretion by insulin: relation to the hyperinsulinemia of obesity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Sensitivity of insulin secretion to feedback inhibition by hyperinsulinaemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

Failure of insulin infusion during euglycemia to influence endogenous basal insulin secretion

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266415

The effect of insulin administration on the insulin content of the pancreas

25 September 2018

1 reference

12 December 2020

Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus

1 reference

12 December 2020

Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription

1 reference

12 December 2020

PROMOTION OF INSULIN SECRETION BY GLUCAGON

1 reference

12 December 2020

Feedback inhibition by biosynthetic human insulin of insulin release in healthy human subjects

1 reference

12 December 2020

Insulin suppresses its own secretion in vivo

1 reference

12 December 2020

Mechanisms of insulin resistance in man. Assessment using the insulin dose-response curve in conjunction with insulin-receptor binding

1 reference

12 December 2020

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB11-1067

1 reference

9 August 2017

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9 August 2017

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