Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase (Q35734793)

10 August 2017

Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase (English)

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10 August 2017

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Amrita Madabushi

1

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10 August 2017

Bor-Jang Hwang

series ordinal

2

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10 August 2017

Jin Jin

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3

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10 August 2017

A-Lien Lu

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4

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10 August 2017

language of work or name

English

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publication date

1 November 2013

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10 August 2017

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10 August 2017

456

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10 August 2017

1

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10 August 2017

89-98

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describes a project that uses

10 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4465237/fullTextXML

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cites work

DNA demethylation dynamics

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Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

12 July 2018

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

12 July 2018

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Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

12 July 2018

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

12 July 2018

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Sirtuin 1 in malignant transformation: friend or foe?

12 July 2018

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Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

12 July 2018

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Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells

12 July 2018

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DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC.

12 July 2018

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Active DNA demethylation: many roads lead to Rome.

12 July 2018

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SIRT1 regulates UV-induced DNA repair through deacetylating XPA

12 July 2018

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Mammalian sirtuins: biological insights and disease relevance

12 July 2018

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Reprogramming towards pluripotency requires AID-dependent DNA demethylation

12 July 2018

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Protein deacetylation by SIRT1: an emerging key post-translational modification in metabolic regulation

12 July 2018

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Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase

12 July 2018

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SIRT1 deacetylates APE1 and regulates cellular base excision repair

12 July 2018

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SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

12 July 2018

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SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

12 July 2018

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Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil

12 July 2018

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SIRT1, is it a tumor promoter or tumor suppressor?

12 July 2018

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

12 July 2018

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Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

12 July 2018

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Coordinating the initial steps of base excision repair. Apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex

12 July 2018

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Transient cyclical methylation of promoter DNA.

12 July 2018

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Cyclical DNA methylation of a transcriptionally active promoter

12 July 2018

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Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development.

12 July 2018

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The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase

12 July 2018

1 reference

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SIRT1 regulates the function of the Nijmegen breakage syndrome protein

12 July 2018

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Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.

12 July 2018

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Sirtuins in mammals: insights into their biological function

12 July 2018

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SIRT1 promotes DNA repair activity and deacetylation of Ku70

12 July 2018

1 reference

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The epigenomics of cancer

12 July 2018

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The enigmatic thymine DNA glycosylase

12 July 2018

1 reference

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Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability

12 July 2018

1 reference

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

12 July 2018

1 reference

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Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation

12 July 2018

1 reference

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Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

12 July 2018

1 reference

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The Sir2 family of protein deacetylases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

5-Fluorouracil: mechanisms of action and clinical strategies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Histone acetylation and deacetylation in yeast

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Functional interactions and signaling properties of mammalian DNA mismatch repair proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

12 July 2018

Thymine DNA glycosylase

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

12 July 2018

https://api.crossref.org/works/10.1042%2FBJ20130670

Base excision repair of DNA in mammalian cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

DNA determinants and substrate specificities of Escherichia coli MutY.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

The CpG dinucleotide and human genetic disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465237

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

12 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20130670

21 January 2018

Identifiers

DOI

10.1042/BJ20130670

1 reference

10 August 2017

1 reference

10 August 2017

1 reference