Targeting signaling factors for degradation, an emerging mechanism for TRAF functions (Q35759267)

10 August 2017

1 reference

title

Targeting signaling factors for degradation, an emerging mechanism for TRAF functions (English)

1 reference

10 August 2017

Xiao-Dong Yang

1

1 reference

10 August 2017

Shao-Cong Sun

series ordinal

2

1 reference

10 August 2017

publication date

1 July 2015

1 reference

10 August 2017

published in

Immunological Reviews

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10 August 2017

volume

266

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10 August 2017

issue

1

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10 August 2017

page(s)

56-71

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Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.

10 August 2017

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2 October 2017

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Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif

2 October 2017

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Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

2 October 2017

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2 October 2017

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Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease

2 October 2017

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The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling

2 October 2017

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Activation of the noncanonical NF-κB pathway by HIV controls a dendritic cell immunoregulatory phenotype.

2 October 2017

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The NS1 protein of influenza A virus blocks RIG-I-mediated activation of the noncanonical NF-κB pathway and p52/RelB-dependent gene expression in lung epithelial cells

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice.

2 October 2017

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2 October 2017

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NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

2 October 2017

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Expanding TRAF function: TRAF3 as a tri-faced immune regulator

2 October 2017

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Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease

2 October 2017

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IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

2 October 2017

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Expanding role of ubiquitination in NF-κB signaling

2 October 2017

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TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling

2 October 2017

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Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling

2 October 2017

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Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis

2 October 2017

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2 October 2017

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2 October 2017

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Oncogenic activation of NF-kappaB.

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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The role of TNF superfamily members in T-cell function and diseases

2 October 2017

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2 October 2017

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Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

2 October 2017

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NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells

2 October 2017

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2 October 2017

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Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

2 October 2017

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A two-step process for thymic regulatory T cell development.

2 October 2017

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2 October 2017

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

2 October 2017

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Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs

2 October 2017

1 reference

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Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

2 October 2017

1 reference

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Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

2 October 2017

1 reference

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TRAF3 and its biological function

2 October 2017

1 reference

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Physiological roles and mechanisms of signaling by TRAF2 and TRAF5.

2 October 2017

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A fourth IkappaB protein within the NF-kappaB signaling module

2 October 2017

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Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

2 October 2017

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Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant

2 October 2017

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The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development

2 October 2017

1 reference

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TRAF3: a new regulator of type I interferons

2 October 2017

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NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6.

2 October 2017

1 reference

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Monocyte and macrophage heterogeneity

2 October 2017

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Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

2 October 2017

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

2 October 2017

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A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.

2 October 2017

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TNF/TNFR family members in costimulation of T cell responses

2 October 2017

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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

2 October 2017

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An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.

2 October 2017

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The multifaceted roles of TRAFs in the regulation of B-cell function.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

De novo synthesized RelB mediates TNF-induced up-regulation of the human polymeric Ig receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

The signaling adaptors and pathways activated by TNF superfamily

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

A novel type of deubiquitinating enzyme

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Interleukin-12 and the regulation of innate resistance and adaptive immunity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Isolation and characterization of two novel A20-like proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

M-1/M-2 macrophages and the Th1/Th2 paradigm

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Opposing roles for TRAF1 in the alternative versus classical NF-κB pathway in T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Inducible activation of RelB in fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Genetic inactivation of TRAF3 in canine and human B-cell lymphoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor".

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Respiratory syncytial virus influences NF-kappaB-dependent gene expression through a novel pathway involving MAP3K14/NIK expression and nuclear complex formation with NF-kappaB2.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473799

Sea-level fingerprinting as a direct test for the source of global meltwater pulse IA.

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FIMR.12311

CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB

21 January 2018

1 reference

12 December 2020

TRAF-mediated TNFR-family signaling

1 reference

12 December 2020

Macrophages: cancer therapy's double-edged sword

1 reference

12 December 2020

A thymic precursor to the NK T cell lineage

1 reference

12 December 2020

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

1 reference

12 December 2020

Impaired function of dendritic cells in alymphoplasia (aly/aly) mice for expansion of CD25+CD4+ regulatory T cells

1 reference

12 December 2020

Identifiers

DOI

10.1111/IMR.12311

1 reference

10 August 2017

1 reference

10 August 2017

1 reference