The MTG proteins: chromatin repression players with a passion for networking (Q35808823)

10 August 2017

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title

The MTG proteins: chromatin repression players with a passion for networking (English)

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10 August 2017

3

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author name string

Stefano Rossetti

series ordinal

1

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PubMed ID

15203199

10 August 2017

André T Hoogeveen

series ordinal

2

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10 August 2017

1 July 2004

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10 August 2017

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10 August 2017

84

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10 August 2017

1

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10 August 2017

1-9

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Genomic medicine--a primer

10 August 2017

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Associations between morphology, karyotype, and clinical features in myeloid leukemias.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Leukaemia/Drosophila homology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Core binding factor and its role in normal hematopoietic development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Function of CBFbeta/Bro proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

RUNX: a trilogy of cancer genes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The ETO (MTG8) gene family

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Transcription factor fusions in acute leukemia: variations on a theme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Oligomerization of ETO is obligatory for corepressor interaction

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Multiple regions of ETO cooperate in transcriptional repression

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Subcellular localization of the oncoprotein MTG8 (CDR/ETO) in neural cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Chromatin disruption and modification

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The language of covalent histone modifications

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Translating the Histone Code

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone methylation: dynamic or static?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone methylation in transcriptional control

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone and chromatin cross-talk

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone deacetylase activity is required for full transcriptional repression by mSin3A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Retinoblastoma protein recruits histone deacetylase to repress transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone deacetylases and transcriptional therapy with their inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Chromatin remodeling, histone modifications, and DNA methylation-how does it all fit together?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Role of co-repressors in transcriptional repression mediated by the t(8;21), t(16;21), t(12;21), and inv(16) fusion proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Epigenetic consequences of AML1-ETO action at the human c-FMS locus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

DNA methylation and chromatin modification.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Increased Methylation of the <i>c-fms</i>Protooncogene in Acute Myelomonocytic Leukemias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Potential involvement of the AML1-MTG8 fusion protein in the granulocytic maturation characteristic of the t(8;21) acute myelogenous leukemia revealed by microarray analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Epigenetic silencing of RNA polymerase I transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Structure and expression of the human MTG8/ETO gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Gene targeting reveals a crucial role for MTG8 in the gut.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

XETOR regulates the size of the proneural domain during primary neurogenesis in Xenopus laevis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Upregulation of class II histone deacetylases mRNA during neural differentiation of cultured rat hippocampal progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Histone deacetylase activity is necessary for oligodendrocyte lineage progression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

ATP-dependent chromatin remodeling factors: nucleosome shufflers with many missions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

The epigenetics of nucleolar dominance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Three classes of C2H2 zinc finger proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Zinc finger proteins: new insights into structural and functional diversity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Having it both ways: transcription factors that bind DNA and RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

RNA-mediated gene silencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Genomics, gene expression and DNA arrays

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Mass spectrometry-based proteomics

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Protein analysis on a proteomic scale

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

From genomics to proteomics

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Genome-wide location and function of DNA binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

Restriction landmark genome scanning.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2004.02.011

10.1016/J.YGENO.2004.02.011

7 January 2021

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15203199