Multiple roles of dihomo-γ-linolenic acid against proliferation diseases (Q35809033)

10 August 2017

2 references

8 February 2021

3 October 2022

Multiple roles of dihomo-γ-linolenic acid against proliferation diseases (English)

1 reference

10 August 2017

dihomo-γ-linolenic acid

1 reference

19 November 2019

1 reference

14 September 2020

1 reference

8 February 2021

Xiaoping Wang

1

1 reference

10 August 2017

Huanping Lin

series ordinal

2

1 reference

10 August 2017

Yan Gu

series ordinal

3

1 reference

10 August 2017

14 February 2012

6 references

Lipids in Health and Disease

10 August 2017

3 April 2019

19 November 2019

14 September 2020

8 February 2021

3 October 2022

6 references

10 August 2017

3 April 2019

19 November 2019

14 September 2020

8 February 2021

3 October 2022

11

1 reference

10 August 2017

25

1 reference

Creative Commons Attribution 2.0 Generic

10 August 2017

5 references

3 April 2019

19 November 2019

14 September 2020

8 February 2021

on focus list of Wikimedia project

3 October 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Triptolide inhibits COX-2 expression by regulating mRNA stability in TNF-α-treated A549 cells

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Role of cyclooxygenase-2 gene polymorphisms in pancreatic carcinogenesis

11 July 2018

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COX-derived prostanoid pathways in gastrointestinal cancer development and progression: novel targets for prevention and intervention

11 July 2018

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11 July 2018

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The role of the EP receptors for prostaglandin E2 in skin and skin cancer

11 July 2018

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Cyclooxygenase-2 and gastric cancer

11 July 2018

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Effect of polyunsaturated fatty acids on drug-sensitive and resistant tumor cells in vitro

11 July 2018

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Regulation of rat brain polyunsaturated fatty acid (PUFA) metabolism during graded dietary n-3 PUFA deprivation

11 July 2018

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Cardioprotective effect of liposomal prostaglandin E1 on a porcine model of myocardial infarction reperfusion no-reflow

11 July 2018

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PLGA microparticles encapsulating prostaglandin E1-hydroxypropyl-β-cyclodextrin (PGE1-HPβCD) complex for the treatment of pulmonary arterial hypertension (PAH).

11 July 2018

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Alpha-linolenic acid intake and 10-year incidence of coronary heart disease and stroke in 20,000 middle-aged men and women in the Netherlands

11 July 2018

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In vitro and in vivo effects of a cyclooxygenase-2 inhibitor nimesulide analog JCC76 in aromatase inhibitors-insensitive breast cancer cells

11 July 2018

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Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression

11 July 2018

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Analysis of omega-3 and omega-6 fatty acid-derived lipid metabolite formation in human and mouse blood samples.

11 July 2018

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Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer

11 July 2018

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Prostaglandin E₂ regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells

11 July 2018

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Induced oxidative stress and cell death in the A549 lung adenocarcinoma cell line by ionizing radiation is enhanced by supplementation with docosahexaenoic acid

11 July 2018

1 reference

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Prostaglandin E1, E2 and their metabolites

11 July 2018

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COX-2-mediated regulation of VEGF-C in association with lymphangiogenesis and lymph node metastasis in lung cancer

11 July 2018

1 reference

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Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study

11 July 2018

1 reference

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Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells

11 July 2018

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11 July 2018

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Prostaglandin E1 encapsulated into lipid nanoparticles improves its anti-inflammatory effect with low side-effect

11 July 2018

1 reference

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Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E2.

11 July 2018

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An overview on the expression of cyclooxygenase-2 in tumors of the head and neck

11 July 2018

1 reference

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Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells

11 July 2018

1 reference

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The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression.

11 July 2018

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Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules

11 July 2018

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Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth

11 July 2018

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The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases

11 July 2018

1 reference

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Can essential fatty acids reduce the burden of disease(s)?

11 July 2018

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Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies.

11 July 2018

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Colon cancer therapy: new perspectives of nutritional manipulations using polyunsaturated fatty acids

11 July 2018

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Gamma linolenic acid: an antiinflammatory omega-6 fatty acid

11 July 2018

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Essential Fatty acids - a review

11 July 2018

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Essential fatty acids: biochemistry, physiology and pathology

11 July 2018

1 reference

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COX-2 inhibitors and metabolism of essential fatty acids

11 July 2018

1 reference

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Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells.

11 July 2018

1 reference

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Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma

11 July 2018

1 reference

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Dietary N-6 and N-3 polyunsaturated fatty acids and prostate cancer risk: a review of epidemiological and experimental evidence

11 July 2018

1 reference

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Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP‐1 cells

11 July 2018

1 reference

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The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy

11 July 2018

1 reference

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Fatty acids, the immune response, and autoimmunity: a question of n-6 essentiality and the balance between n-6 and n-3.

11 July 2018

1 reference

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Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2

11 July 2018

1 reference

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Significance of lipoxygenase-derived monohydroxy fatty acids in cutaneous biology

11 July 2018

1 reference

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Cyclooxygenases: structural, cellular, and molecular biology

11 July 2018

1 reference

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The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins

11 July 2018

1 reference

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Importance of dietary gamma-linolenic acid in human health and nutrition

11 July 2018

1 reference

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The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells

11 July 2018

1 reference

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Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

In vivo and in vitro biotransformation of the lithium salt of gamma-linolenic acid by three human carcinomas

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Differential effects of prostaglandin E1 and prostaglandin E2 on growth and differentiation of murine myeloid leukemic cell line, M1.

11 July 2018

1 reference

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Prostanoid receptors and their biological actions

11 July 2018

1 reference

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Regulation of agonist-induced prostaglandin E1 versus prostaglandin E2 production. A mass analysis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Cellular interactions between n-6 and n-3 fatty acids: a mass analysis of fatty acid elongation/desaturation, distribution among complex lipids, and conversion to eicosanoids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

11 July 2018

1 reference

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Antithrombotic potential of dihomo-gamma-linolenic acid in man

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

The relationships between erythrocyte membrane n-6 to n-3 polyunsaturated fatty acids ratio and blood lipids and C-reactive protein in Chinese adults: an observational study.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Effects of Dietary α-Linolenic Acid (18:3n-3)/Linoleic Acid (18:2n-6) Ratio on Fatty Acid Metabolism in Murray Cod (Maccullochella peelii peelii)

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant

25 September 2018

1 reference

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Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Oral supplementation with dihomo-gamma-linolenic acid-enriched oil altered serum fatty acids in healthy men.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Subchronic (13-week) oral toxicity study of dihomo-gamma-linolenic acid (DGLA) oil in rats

25 September 2018

1 reference

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Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Effects of selective COX-2 and 5-LOX inhibition on prostaglandin and leukotriene synthesis in ductal pancreatic cancer in Syrian hamster

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-li

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

The correlation between cyclooxygenase-2 expression and hepatocellular carcinogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites?

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

A novel 15-hydroxyeicosatrienoic acid-substituted diacylglycerol (15-HETrE-DAG) selectively inhibits epidermal protein kinase C-beta

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295719

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1476-511X-11-25

PGE1 and PGE2 modify platelet function through different prostanoid receptors

21 January 2018

1 reference

12 December 2020

The induction of apoptosis in human cervical carcinoma (HeLa) cells by gamma-linolenic acid

1 reference

12 December 2020

gamma-Linolenic acid treatment of rheumatoid arthritis. A randomized, placebo-controlled trial

1 reference

12 December 2020

Trans-18:1 and CLA isomers in rumen and duodenal digesta of bulls fed n-3 and n-6 PUFA-based diets

1 reference

12 December 2020

Plasma n-3 and n-6 fatty acids and the incidence of atrial fibrillation following coronary artery bypass graft surgery

1 reference

12 December 2020

Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro

1 reference

12 December 2020

Transcription factors coupled to the cAMP-signalling pathway

1 reference

12 December 2020

Regulation of desmosomal cell adhesion in human tumour cells by polyunsaturated fatty acids

1 reference

12 December 2020

Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells: relationship to free radicals and lipid peroxidation and its modulation by calmodulin antagonists

1 reference

12 December 2020

Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells in vitro

1 reference

12 December 2020

Apoptosis. p53 and PUMA: a deadly duo

1 reference

12 December 2020

Identifiers

DOI

10.1186/1476-511X-11-25

1 reference

Dimensions Publication ID

10 August 2017

0 references

1 reference

10 August 2017

PubMed publication ID

22333072

1 reference