Interferon-γ-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn. (Q39592093)

13 September 2017

Interferon-γ-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn. (English)

1 reference

13 September 2017

1 reference

David Smyth

1

1 reference

13 September 2017

Van Phan

series ordinal

2

1 reference

13 September 2017

Arthur Wang

series ordinal

3

1 reference

13 September 2017

Derek M McKay

series ordinal

4

1 reference

13 September 2017

14 February 2011

1 reference

13 September 2017

Laboratory Investigation

1 reference

13 September 2017

91

1 reference

13 September 2017

5

1 reference

13 September 2017

764-777

1 reference

https://scigraph.springernature.com/pub.10.1038/labinvest.2010.208

13 September 2017

0 references

cites work

Intestinal mucosal barrier function in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma regulation of intestinal epithelial permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon gamma induces translocation of commensal Escherichia coli across gut epithelial cells via a lipid raft-mediated process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Phosphatidylinositol 3'-kinase is a critical mediator of interferon-gamma-induced increases in enteric epithelial permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

How cells respond to interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Regulation, substrates and functions of src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

SFK-STAT pathway: an alternative and important way to malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

c-Src is required for tropomyosin receptor kinase C (TrkC)-induced activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Src regulates cell cycle protein expression and renal epithelial cell proliferation via PI3K/Akt signaling-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Role of Fyn and PI3K in H2O2-induced inhibition of apical Cl-/OH- exchange activity in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Hydrogen peroxide inhibits Ca2+-dependent chloride secretion across colonic epithelial cells via distinct kinase signaling pathways and ion transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Green tea polyphenol (-)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-gamma but not by IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

The IFN gamma receptor: a paradigm for cytokine receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

The Stat1 binding motif of the interferon-gamma receptor is sufficient to mediate Stat5 activation and its repression by SOCS3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Adhesion signaling - crosstalk between integrins, Src and Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Src, cortactin and Arp2/3 complex are required for E-cadherin-mediated internalization of Listeria into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Tyrosine phosphorylation of occludin attenuates its interactions with ZO-1, ZO-2, and ZO-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Clustering transfers the translocated Escherichia coli receptor into lipid rafts to stimulate reversible activation of c-Fyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Interferon-gamma and interleukin-12 pathway defects and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

Mouse models of intestinal inflammation as tools to understand the pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

inferred from DOI database lookup

7 January 2021

based on heuristic

Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

inferred from DOI database lookup

7 January 2021

based on heuristic

Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.208

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LABINVEST.2010.208

1 reference

13 September 2017

1 reference