TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion (Q35883901)

10 August 2017

TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion (English)

1 reference

10 August 2017

4

Rosemary J Akhurst

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10 August 2017

Samy Lamouille

1

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10 August 2017

Erin Connolly

series ordinal

2

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10 August 2017

James W Smyth

series ordinal

3

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10 August 2017

Rik Derynck

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5

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10 August 2017

language of work or name

English

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publication date

7 March 2012

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10 August 2017

Journal of Cell Science

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10 August 2017

125

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10 August 2017

Pt 5

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10 August 2017

1259-1273

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describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3324583/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Biomarkers for epithelial-mesenchymal transitions

27 July 2018

1 reference

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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

27 July 2018

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27 July 2018

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TGF-beta-mediated activation of RhoA signalling is required for efficient (V12)HaRas and (V600E)BRAF transformation

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Paxillin comes of age

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Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

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Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

27 July 2018

1 reference

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Genetic determinants of cancer metastasis

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

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1 reference

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Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity

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Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

27 July 2018

1 reference

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mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

27 July 2018

1 reference

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27 July 2018

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Complex networks orchestrate epithelial-mesenchymal transitions

27 July 2018

1 reference

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Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

27 July 2018

1 reference

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Cooperative effects of Rho and mechanical stretch on stress fiber organization

27 July 2018

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Specificity and versatility in tgf-beta signaling through Smads

27 July 2018

1 reference

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TGF-beta and epithelial-to-mesenchymal transitions

27 July 2018

1 reference

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Non-Smad TGF-beta signals

27 July 2018

1 reference

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Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor

27 July 2018

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

27 July 2018

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

27 July 2018

1 reference

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

27 July 2018

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Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

27 July 2018

1 reference

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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

27 July 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

27 July 2018

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

27 July 2018

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

27 July 2018

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The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324583

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

27 July 2018

1 reference

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Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.

27 July 2018

1 reference

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TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

27 July 2018

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Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice

27 July 2018

1 reference

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mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

27 July 2018

1 reference

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Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer

24 September 2018

1 reference

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EMT, the cytoskeleton, and cancer cell invasion

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324583

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3324583

24 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399812

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.095299

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22399812

1 reference