The role of functional and molecular imaging in cancer drug discovery and development (Q35968111)

11 August 2017

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title

The role of functional and molecular imaging in cancer drug discovery and development (English)

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11 August 2017

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B M Seddon

1

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PubMed ID

15572335

11 August 2017

P Workman

series ordinal

2

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PubMed ID

15572335

11 August 2017

language of work or name

English

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publication date

1 January 2003

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British Journal of Radiology

11 August 2017

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11 August 2017

76 Spec No 2

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11 August 2017

S128-38

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Essential drugs for cancer therapy: a World Health Organization consultation

11 August 2017

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Anticancer agents targeting signaling molecules and cancer cell environment: challenges for drug development?

21 January 2018

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New drug targets for genomic cancer therapy: successes, limitations, opportunities and future challenges.

21 January 2018

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The price of innovation: new estimates of drug development costs

21 January 2018

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Discovering novel chemotherapeutic drugs for the third millennium

21 January 2018

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Initial sequencing and analysis of the human genome

21 January 2018

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The Sequence of the Human Genome

21 January 2018

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21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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Control of the cell cycle and apoptosis

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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21 January 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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Finding the needle in the haystack: why high-throughput screening is good for your health

21 January 2018

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How much gets there and what does it do?: The need for better pharmacokinetic and pharmacodynamic endpoints in contemporary drug discovery and development

21 January 2018

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Telomerase as a Target for Cancer Immunotherapy

21 January 2018

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Reporting results of cancer treatment

21 January 2018

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

21 January 2018

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Measurement of tissue perfusion by dynamic computed tomography

21 January 2018

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Measuring changes in human tumour vasculature in response to therapy using functional imaging techniques

21 January 2018

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Functional MRI for anticancer therapy assessment

21 January 2018

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MR imaging characterization of microvessels in experimental breast tumors by using a particulate contrast agent with histopathologic correlation.

21 January 2018

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Non-invasive vascular imaging: assessing tumour vascularity

21 January 2018

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Functional ultrasound methods in oncological imaging

21 January 2018

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The physical basis of diffusion-weighted MRI.

21 January 2018

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Basic principles of diffusion-weighted imaging

21 January 2018

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Early increases in breast tumor xenograft water mobility in response to paclitaxel therapy detected by non-invasive diffusion magnetic resonance imaging

21 January 2018

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Diffusion-weighted magnetic resonance imaging for monitoring diffusion changes in rectal carcinoma during combined, preoperative chemoradiation: preliminary results of a prospective study

21 January 2018

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Diffusion MRI for prediction of response of rectal cancer to chemoradiation

21 January 2018

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Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation

21 January 2018

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Magnetic resonance imaging techniques for monitoring changes in tumor oxygenation and blood flow.

21 January 2018

1 reference

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Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging.

21 January 2018

1 reference

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Non-invasive 19F-NMRS of 5-fluorouracil in pharmacokinetics and pharmacodynamic studies

21 January 2018

1 reference

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19F-MRS studies of fluorinated drugs in humans

21 January 2018

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Application of magnetic resonance techniques for imaging tumour physiology

21 January 2018

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https://api.crossref.org/works/10.1259%2FBJR%2F27373639

Tumor oximetry: demonstration of an enhanced dynamic mapping procedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate R3327-AT1 rat tumor

21 January 2018

1 reference

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Tumor oxygen dynamics with respect to growth and respiratory challenge: investigation of the Dunning prostate R3327-HI tumor

21 January 2018

1 reference

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Evaluating tumor biology and oncological disease with positron-emission tomography

21 January 2018

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Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study

21 January 2018

1 reference

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2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337.

21 January 2018

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Scaling down imaging: molecular mapping of cancer in mice

21 January 2018

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Imaging transgene expression with radionuclide imaging technologies

21 January 2018

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HSP90 as a new therapeutic target for cancer therapy: the story unfolds

21 January 2018

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Hsp90 inhibitors as novel cancer chemotherapeutic agents

21 January 2018

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The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

21 January 2018

1 reference

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Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.

21 January 2018

1 reference

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DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

21 January 2018

1 reference

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Use of radiolabelled choline as a pharmacodynamic marker for the signal transduction inhibitor geldanamycin

21 January 2018

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

1 reference

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Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

21 January 2018

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Activation of the HIF pathway in cancer

21 January 2018

1 reference

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HIF-1 and mechanisms of hypoxia sensing

21 January 2018

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Hyperbaric oxygen: the Medical Research Council trials and their clinical significance

21 January 2018

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The role of hypoxia-activated prodrugs in cancer therapy

21 January 2018

1 reference

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The novel fluorinated 2-nitroimidazole hypoxia probe SR-4554: reductive metabolism and semiquantitative localisation in human ovarian cancer multicellular spheroids as measured by electron energy loss spectroscopic analysis

21 January 2018

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Signalling the fat controller

21 January 2018

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21 January 2018

Identifiers

DOI

10.1259/BJR/27373639

1 reference

11 August 2017

1 reference

PubMed ID

15572335