Building an antibody factory: a job for the unfolded protein response (Q35990295)

11 August 2017

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title

Building an antibody factory: a job for the unfolded protein response (English)

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11 August 2017

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Joseph W Brewer

1

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11 August 2017

Linda M Hendershot

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

1 January 2005

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11 August 2017

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11 August 2017

6

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11 August 2017

1

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11 August 2017

23-29

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https://scigraph.springernature.com/pub.10.1038/ni1149

11 August 2017

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cites work

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

1 reference

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

21 January 2018

1 reference

Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast

21 January 2018

1 reference

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

21 January 2018

1 reference

tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

21 January 2018

1 reference

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

1 reference

IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae

21 January 2018

1 reference

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

21 January 2018

1 reference

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

21 January 2018

1 reference

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

21 January 2018

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Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

1 reference

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

21 January 2018

1 reference

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

21 January 2018

1 reference

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

1 reference

Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress

21 January 2018

1 reference

PERK mediates cell-cycle exit during the mammalian unfolded protein response

21 January 2018

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Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses

21 January 2018

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

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Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinately

21 January 2018

1 reference

Biogenesis of the endoplasmic reticulum in activated B lymphocytes: temporal relationships between the induction of protein N-glycosylation activity and the biosynthesis of membrane protein and phospholipid.

21 January 2018

1 reference

Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion

21 January 2018

1 reference

Immunoglobulin heavy chain binding protein

21 January 2018

1 reference

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein

21 January 2018

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Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

21 January 2018

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Defective co-translational formation of disulphide bonds in protein disulphide-isomerase-deficient microsomes.

21 January 2018

1 reference

Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44

21 January 2018

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The contribution of ER quality control to the biologic functions of secretory IgM.

21 January 2018

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Plasma cell differentiation requires the transcription factor XBP-1

21 January 2018

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Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

21 January 2018

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

21 January 2018

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Activation of an unfolded protein response during differentiation of antibody-secreting B cells.

21 January 2018

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ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

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Stress-induced gene expression requires programmed recovery from translational repression

21 January 2018

1 reference

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 January 2018

1 reference

A transgenic mouse model for monitoring endoplasmic reticulum stress

21 January 2018

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

21 January 2018

1 reference

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

1 reference

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

21 January 2018

1 reference

P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling

21 January 2018

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Protein serine/threonine phosphatase Ptc2p negatively regulates the unfolded-protein response by dephosphorylating Ire1p kinase.

21 January 2018

1 reference

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

21 January 2018

1 reference

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

21 January 2018

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Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

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Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor

21 January 2018

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Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells

21 January 2018

1 reference

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

21 January 2018

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Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation

21 January 2018

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Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1

21 January 2018

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Repression of c-myc is necessary but not sufficient for terminal differentiation of B lymphocytes in vitro

21 January 2018

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BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells

21 January 2018

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Development of rough endoplasmic reticulum in mouse splenic lymphocytes stimulated by mitogens

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

A role for the unfolded protein response in optimizing antibody secretion

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI1149

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Dimensions Publication ID

11 August 2017

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1 reference