Modulation of angiogenesis with siRNA inhibitors for novel therapeutics (Q36067845)

12 August 2017

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title

Modulation of angiogenesis with siRNA inhibitors for novel therapeutics (English)

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12 August 2017

Patrick Y Lu

1

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12 August 2017

Frank Y Xie

series ordinal

2

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12 August 2017

Martin C Woodle

series ordinal

3

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12 August 2017

publication date

1 March 2005

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Trends in Molecular Medicine

12 August 2017

published in

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12 August 2017

volume

11

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12 August 2017

issue

3

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12 August 2017

page(s)

104-113

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Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells

12 August 2017

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Basement membranes: structure, assembly and role in tumour angiogenesis

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PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor

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Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

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Angiogenesis inhibition by the novel VEGF receptor tyrosine kinase inhibitor, PTK787/ZK222584, causes significant anti-arthritic effects in models of rheumatoid arthritis

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c-Src-dependent cross-talk between CEACAM6 and alphavbeta3 integrin enhances pancreatic adenocarcinoma cell adhesion to extracellular matrix components

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12 December 2020

TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor

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12 December 2020

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

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12 December 2020

Novel tumor necrosis factor alpha-regulated genes in rheumatoid arthritis.

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12 December 2020

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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VEGF gene polymorphisms and susceptibility to rheumatoid arthritis

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Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion.

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12 December 2020

Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus

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12 December 2020

Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells

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Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway

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12 December 2020

Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro

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Akt is an endogenous inhibitor toward tumor necrosis factor-related apoptosis inducing ligand-mediated apoptosis in rheumatoid synovial cells

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The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress

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Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein

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12 December 2020

SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth.

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12 December 2020

Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro

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12 December 2020

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

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12 December 2020

Lack of interferon response in animals to naked siRNAs

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12 December 2020

ILKAP regulates ILK signaling and inhibits anchorage-independent growth

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12 December 2020

Role of metalloprotease disintegrin ADAM12 in determination of quiescent reserve cells during myogenic differentiation in vitro.

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12 December 2020

Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway

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Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling

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Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

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12 December 2020

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

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Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells

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12 December 2020

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12 December 2020

RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells.

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12 December 2020

The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged

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12 December 2020

IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.

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12 December 2020

Clinical translation of angiogenesis inhibitors

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12 December 2020

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

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12 December 2020

Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC

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12 December 2020

Smad2 mediates Erk1/2 activation by TGF-beta1 in suspended, but not in adherent, gastric carcinoma cells.

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12 December 2020

A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics

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12 December 2020

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12 December 2020

DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner

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12 December 2020

RNA interference for HIF-1alpha inhibits its downstream signalling and affects cellular proliferation

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12 December 2020

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

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12 December 2020

Pharmaceutical prospects for RNA interference.

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12 December 2020

VEGF induces Mcl-1 up-regulation and protects multiple myeloma cells against apoptosis

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12 December 2020

Matrix Metalloproteinase-9 Silencing by RNA Interference Triggers the Migratory-adhesive Switch in Ewing's Sarcoma Cells

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12 December 2020

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12 December 2020

Lymphangiogenesis and cancer metastasis

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12 December 2020

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

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12 December 2020

siRNA agents inhibit oncogene expression and attenuate human tumor cell growth

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12 December 2020

Progestin-dependent induction of vascular endothelial growth factor in human breast cancer cells: preferential regulation by progesterone receptor B.

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12 December 2020

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

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12 December 2020

Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells

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12 December 2020

RNA interference may be more potent than antisense RNA in human cancer cell lines

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12 December 2020

10.1016/J.MOLMED.2005.01.005

Identifiers

DOI

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12 August 2017

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