Oxysterols and oxysterol binding proteins: role in lipid metabolism and atherosclerosis. (Q36071531)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768828%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

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title

Oxysterols and oxysterol binding proteins: role in lipid metabolism and atherosclerosis (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768828%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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1

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9 January 2020

author name string

Markku Lehto

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768828%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

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publication date

1 January 2004

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9 January 2020

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9 January 2020

volume

36

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9 January 2020

page(s)

562-572

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9 January 2020

issue

8

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Oxysterols: friends, foes, or just fellow passengers?

9 January 2020

cites work

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The liver X receptor gene team: potential new players in atherosclerosis

21 January 2018

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Liver X receptors: new players in atherogenesis?

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LXRs: new therapeutic targets in atherosclerosis?

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Oxysterol biosynthetic enzymes

21 January 2018

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21 January 2018

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Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation

21 January 2018

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Metabolism of 4 beta -hydroxycholesterol in humans.

21 January 2018

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Transport of side-chain oxidized oxysterols in the human circulation.

21 January 2018

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Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol.

21 January 2018

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Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols

21 January 2018

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Mechanisms of oxysterol-induced apoptosis

21 January 2018

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7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein

21 January 2018

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Antagonist action of cholesterol towards the toxicity of hydroxysterols on cultured hepatoma cells

21 January 2018

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Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate

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Trojan horse-like behavior of a biologically representative mixture of oxysterols

21 January 2018

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Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins

21 January 2018

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Oxidation of low-density lipoprotein by human monocyte-macrophages results in toxicity to the oxidising culture.

21 January 2018

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Apoptotic death of inflammatory cells in human atheroma

21 January 2018

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Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque

21 January 2018

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7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta

21 January 2018

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Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism

21 January 2018

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Increased plasma 7 beta-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease.

21 January 2018

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Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols

21 January 2018

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 January 2018

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Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

21 January 2018

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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 January 2018

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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

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Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 January 2018

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Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

21 January 2018

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21 January 2018

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Phospholipid transfer protein is regulated by liver X receptors in vivo

21 January 2018

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The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions

21 January 2018

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Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

21 January 2018

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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

21 January 2018

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21 January 2018

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Identification of macrophage liver X receptors as inhibitors of atherosclerosis

21 January 2018

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

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21 January 2018

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21 January 2018

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The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes.

21 January 2018

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Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.

21 January 2018

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Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain

21 January 2018

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Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol

21 January 2018

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Molecular machinery for non-vesicular trafficking of ceramide

21 January 2018

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The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct

21 January 2018

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Oxysterol binding protein and its homologues: new regulatory factors involved in lipid metabolism

21 January 2018

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VAMP-associated protein-A regulates partitioning of oxysterol-binding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus.

21 January 2018

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Oxysterol binding proteins: in more than one place at one time?

21 January 2018

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A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution

21 January 2018

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10.1080/07853890410018907

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768828%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference