NOX4 pathway as a source of selective insulin resistance and responsiveness (Q36099612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

NOX4 pathway as a source of selective insulin resistance and responsiveness (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Xiangdong Wu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

9 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

number of pages

10

1 reference

Arteriosclerosis, Thrombosis, and Vascular Biology

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

1236-1245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3398464/fullTextXML

inferred from PubMed Central ID database lookup

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Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome

2 October 2017

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2 October 2017

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2 October 2017

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Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.

2 October 2017

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Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

2 October 2017

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NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

2 October 2017

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The neck of caveolae is a distinct plasma membrane subdomain that concentrates insulin receptors in 3T3-L1 adipocytes

2 October 2017

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2 October 2017

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Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

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2 October 2017

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2 October 2017

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2 October 2017

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Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

2 October 2017

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Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.

2 October 2017

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The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway

2 October 2017

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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

2 October 2017

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Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

2 October 2017

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

2 October 2017

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Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

2 October 2017

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The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals

2 October 2017

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The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction

2 October 2017

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The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer

2 October 2017

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Role of caveolin and caveolae in insulin signaling and diabetes

2 October 2017

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Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

2 October 2017

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2 October 2017

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

2 October 2017

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2 October 2017

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Insulin-regulated gene expression

2 October 2017

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Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes

2 October 2017

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Role of LXRs in control of lipogenesis

2 October 2017

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Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

2 October 2017

1 reference

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Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

2 October 2017

1 reference

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Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

2 October 2017

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Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase

2 October 2017

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2 October 2017

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ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

2 October 2017

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

2 October 2017

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

2 October 2017

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A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast

2 October 2017

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ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

2 October 2017

1 reference

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The response-to-retention hypothesis of early atherogenesis

2 October 2017

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Inhibitors of NADPH oxidase as guides to its mechanism

2 October 2017

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Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase

2 October 2017

1 reference

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The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Circulating tissue factor procoagulant activity and thrombin generation in patients with type 2 diabetes: effects of insulin and glucose

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Protein-tyrosine phosphatase activity in human adipocytes is strongly correlated with insulin-stimulated glucose uptake and is a target of insulin-induced oxidative inhibition

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Chylomicron remnant metabolism studied with a new breath test in postmenopausal women with and without type 2 diabetes mellitus.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Identification of multifunctional ATP-citrate lyase kinase as the alpha-isoform of glycogen synthase kinase-3

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

ACCORD and Risk-Factor Control in Type 2 Diabetes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Inverse association between liver fat content and hepatic glucose uptake in patients with type 2 diabetes mellitus

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

In vivo effects of insulin and free fatty acids on matrix metalloproteinases in rat aorta

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

mTORC2 Caught in a SINful Akt.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

ERK1/2 mediates insulin stimulation of Na(+),K(+)-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Effect of physiological hyperinsulinemia on gluconeogenesis in nondiabetic subjects and in type 2 diabetic patients.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398464

Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials

5 December 2018

1 reference

12 December 2020

Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed ham

1 reference

12 December 2020

Cardiac output and renal function during insulin hypertension in Sprague-Dawley rats

1 reference

12 December 2020

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects

1 reference

12 December 2020

Endogenous hydrogen peroxide and peroxidative metabolism in adipocytes in response to insulin and sulfhydryl reagents

1 reference

12 December 2020

Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylat

1 reference

12 December 2020

Antidiuresis associated with administration of insulin

1 reference

12 December 2020

10.1161/ATVBAHA.111.244525

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328777%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22328777

1 reference