SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. (Q36119281)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846172%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB (English)

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7 January 2020

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3

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7 January 2020

author name string

Qingyang Gu

series ordinal

1

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7 January 2020

G Tim Bowden

series ordinal

2

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7 January 2020

Yi Sun

series ordinal

4

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7 January 2020

language of work or name

English

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publication date

1 September 2007

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7 January 2020

number of pages

15

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inferred from page(s)

published in

Journal of Cell Biology

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7 January 2020

volume

178

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7 January 2020

issue

6

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7 January 2020

page(s)

1009-1023

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Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role

7 January 2020

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Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1

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2 October 2017

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2 October 2017

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2 October 2017

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AP-1 in cell proliferation and survival

2 October 2017

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Elevated expression of SAG/ROC2/Rbx2/Hrt2 in human colon carcinomas: SAG does not induce neoplastic transformation, but antisense SAG transfection inhibits tumor cell growth

2 October 2017

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Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulation

2 October 2017

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2 October 2017

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The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

2 October 2017

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Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

2 October 2017

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ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

2 October 2017

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Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

2 October 2017

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SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents

2 October 2017

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

2 October 2017

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Mdm2 promotes the rapid degradation of p53

2 October 2017

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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

2 October 2017

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2 October 2017

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2 October 2017

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SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation

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Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model

2 July 2018

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Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene

2 July 2018

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Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate

2 July 2018

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Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

2 July 2018

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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

2 July 2018

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Targeting beta-transducin repeat-containing protein E3 ubiquitin ligase augments the effects of antitumor drugs on breast cancer cells

23 September 2018

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Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

23 September 2018

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SAG attenuates apoptotic cell death caused by simulated ischaemia/reoxygenation in rat cardiomyocytes.

23 September 2018

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Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model.

23 September 2018

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Attenuation of ischemia-induced mouse brain injury by SAG, a redox-inducible antioxidant protein

23 September 2018

1 reference

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Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling

23 September 2018

1 reference

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c-fos is required for malignant progression of skin tumors.

23 September 2018

1 reference

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Comparison of the tumor-initiating activity of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene in female SENCAR and CD-1 mice

23 September 2018

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[1] Isolation and utilization of epidermal keratinocytes for oncogene research

23 September 2018

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Crossref

https://api.crossref.org/works/10.1083%2FJCB.200612067

Expression of the sensitive to apoptosis gene, SAG, as a prognostic marker in nonsmall cell lung cancer

21 January 2018

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PubMed

12 December 2020

Changes in keratin gene expression during terminal differentiation of the keratinocyte

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PubMed

12 December 2020

FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin

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PubMed

12 December 2020

Identifiers

DOI

10.1083/JCB.200612067

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846172%20AND%20SRC:MED&resulttype=core&format=json

release_33g2yvojpff6rexw3nhqfrwlfq

7 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/33g2yvojpff6rexw3nhqfrwlfq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846172%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference