Improved affinity at the cost of decreased specificity: a recurring theme in PDZ-peptide interactions (Q36150850)

12 August 2017

Improved affinity at the cost of decreased specificity: a recurring theme in PDZ-peptide interactions (English)

1 reference

12 August 2017

Ylva Ivarsson

4

0 references

author name string

O Andreas Karlsson

1

1 reference

12 August 2017

Gustav N Sundell

2

1 reference

12 August 2017

Eva Andersson

3

1 reference

12 August 2017

Per Jemth

5

1 reference

12 August 2017

language of work or name

English

0 references

publication date

3 October 2016

1 reference

12 August 2017

1 reference

12 August 2017

6

1 reference

12 August 2017

34269

1 reference

Creative Commons Attribution 4.0 International

12 August 2017

start time

3 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Design of a PDZbody, a bivalent binder of the E6 protein from human papillomavirus

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Proteomics. Tissue-based map of the human proteome

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A structural portrait of the PDZ domain family

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Alteration of the C-terminal ligand specificity of the erbin PDZ domain by allosteric mutational effects

2 October 2017

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Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

2 October 2017

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HPV E6 oncoprotein as a potential therapeutic target in HPV related cancers

2 October 2017

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Energetic pathway sampling in a protein interaction domain.

2 October 2017

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Primary human cervical carcinoma cells require human papillomavirus E6 and E7 expression for ongoing proliferation

2 October 2017

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The multiple-specificity landscape of modular peptide recognition domains

2 October 2017

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Human papillomavirus oncoproteins: pathways to transformation

2 October 2017

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The Plastic Energy Landscape of Protein Folding: A TRIANGULAR FOLDING MECHANISM WITH AN EQUILIBRIUM INTERMEDIATE FOR A SMALL PROTEIN DOMAIN

2 October 2017

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SAP97 regulates Kir2.3 channels by multiple mechanisms

2 October 2017

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Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity

2 October 2017

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A sequential binding mechanism in a PDZ domain.

2 October 2017

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Papillomaviruses in the causation of human cancers - a brief historical account

2 October 2017

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Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis

2 October 2017

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Human papillomaviruses, cervical cancer and cell polarity

2 October 2017

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A specificity map for the PDZ domain family

2 October 2017

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Contextual specificity in peptide-mediated protein interactions

2 October 2017

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PDZ domain binding selectivity is optimized across the mouse proteome

2 October 2017

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PDZ domains: folding and binding

2 October 2017

1 reference

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Structures of a human papillomavirus (HPV) E6 polypeptide bound to MAGUK proteins: mechanisms of targeting tumor suppressors by a high-risk HPV oncoprotein

2 October 2017

1 reference

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A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.

2 October 2017

1 reference

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p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

2 October 2017

1 reference

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WebLogo: A Sequence Logo Generator

2 October 2017

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Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein

2 October 2017

1 reference

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Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins

2 October 2017

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Optimization of specificity in a cellular protein interaction network by negative selection

2 October 2017

1 reference

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PDZ Domain Proteins: Plug and Play!

2 October 2017

1 reference

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Mechanism and role of PDZ domains in signaling complex assembly

2 October 2017

1 reference

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Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

2 October 2017

1 reference

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Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

2 October 2017

1 reference

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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

2 October 2017

1 reference

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Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Sequence-specific long range networks in PSD-95/discs large/ZO-1 (PDZ) domains tune their binding selectivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Using circular dichroism collected as a function of temperature to determine the thermodynamics of protein unfolding and binding interactions

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

The study of bimolecular reactions under non-pseudo-first order conditions.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

Coevolution of PDZ domain-ligand interactions analyzed by high-throughput phage display and deep sequencing

23 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046105

21 October 2018

https://api.crossref.org/works/10.1038%2FSREP34269

Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins

21 January 2018

1 reference

PubMed

12 December 2020

The transition state of coupled folding and binding for a flexible β-finger

1 reference

PubMed

12 December 2020

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/SREP34269

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

27694853

1 reference