Negative selection imparts peptide specificity to the mature T cell repertoire (Q36161289)

12 August 2017

Negative selection imparts peptide specificity to the mature T cell repertoire (English)

1 reference

12 August 2017

Philippa Marrack

5

0 references

John Kappler

series ordinal

4

object named as

John Kappler

1 reference

12 August 2017

3

Janice White

1 reference

12 August 2017

1

Eric S Huseby

1 reference

12 August 2017

Frances Crawford

2

1 reference

PMCID

208798

12 August 2017

language of work or name

English

0 references

publication date

22 September 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

12 August 2017

100

1 reference

12 August 2017

20

1 reference

12 August 2017

11565-11570

1 reference

The somatic generation of immune recognition

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

CDR3 loop flexibility contributes to the degeneracy of TCR recognition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Not just any T cell receptor will do.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

A novel family of retroviral vectors for the rapid production of complex stable cell lines.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Population biology of lymphocytes: the flight for survival

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Production and characterization of T cell hybridomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Mice lacking all conventional MHC class II genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

A basis for alloreactivity: MHC helical residues broaden peptide recognition by the TCR.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Selection of antigen-specific T cells by a single IEk peptide combination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

How many thymocytes audition for selection?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Peptide-independent recognition by alloreactive cytotoxic T lymphocytes (CTL).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Quantitative impact of thymic clonal deletion on the T cell repertoire

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Molecular basis for the recognition of two structurally different major histocompatibility complex/peptide complexes by a single T-cell receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Specificity and degeneracy of minor histocompatibility antigen-specific MHC-restricted CTL.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

The molecular basis of allorecognition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Recognition of multiple peptide cores by a single T cell receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Sequence analysis of peptides bound to MHC class II molecules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Comparison of peptides bound to spleen and thymus class II.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Production of soluble MHC class II proteins with covalently bound single peptides

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103).

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

The T cell repertoire may be biased in favor of MHC recognition.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Selection of amino acid sequences in the beta chain of the T cell antigen receptor

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells.

2 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

The repertoire of T cells shaped by a single MHC/peptide ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

T cells down-modulate peptide-MHC complexes on APCs in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Failure to find holes in the T-cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Immunological adjuvants promote activated T cell survival via induction of Bcl-3.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208798

T Cells Can Be Activated by Peptides That Are Unrelated in Sequence to Their Selecting Peptide

23 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Presidential Address to The American Association of Immunologists: Major Histocompatibility Complex Proteins and TCRs: Do They Really Go Together Like a Horse and Carriage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Self tolerance is H–2-restricted

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Evidence from in vitro studies that tolerance to self antigens is MHC-restricted

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

A very high level of crossreactivity is an essential feature of the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Ligand thresholds at different stages of T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Selection of a broad repertoire of CD4+ T cells in H-2Ma0/0 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Cell Cycle Checkpoint Control Is Bypassed by Human Papillomavirus Oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

The fine specificity of antigen and la determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

High determinant density may explain the phenomenon of alloreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934636100

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14504410

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1934636100

1 reference

12 August 2017

0 references

1 reference

12 August 2017

1 reference

PMCID

208798