CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10. (Q36180198)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22570418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10 (English)

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31 January 2020

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3

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31 January 2020

author name string

Manpreet Kaur

1

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31 January 2020

Md Muntaz Khan

2

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31 January 2020

Aparna Sharma

4

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31 January 2020

Sandeep Saxena

5

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31 January 2020

language of work or name

English

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publication date

8 May 2012

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31 January 2020

number of pages

15

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based on heuristic

inferred from page(s)

published in

Nucleic Acids Research

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31 January 2020

volume

40

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31 January 2020

page(s)

7332-7346

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31 January 2020

issue

15

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Creative Commons Attribution-NonCommercial 3.0 Unported

31 January 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

1 October 2017

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PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

1 October 2017

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CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation

1 October 2017

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Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development

1 October 2017

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VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation

1 October 2017

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Domain architecture and biochemical characterization of vertebrate Mcm10

1 October 2017

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Hexameric ring structure of human MCM10 DNA replication factor

1 October 2017

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APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase

1 October 2017

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HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

1 October 2017

1 reference

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DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

1 October 2017

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The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

1 October 2017

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Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

1 October 2017

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A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta

1 October 2017

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HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

1 October 2017

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The role of Vpr in the regulation of HIV-1 gene expression

1 October 2017

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DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint

1 October 2017

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Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

1 October 2017

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A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

1 October 2017

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Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

1 October 2017

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Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast

1 October 2017

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A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.

1 October 2017

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1 October 2017

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The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

1 October 2017

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PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination

1 October 2017

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Function and regulation of cullin-RING ubiquitin ligases

1 October 2017

1 reference

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Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha.

1 October 2017

1 reference

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Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage

1 October 2017

1 reference

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Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

1 October 2017

1 reference

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The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase

1 October 2017

1 reference

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DNA replication in eukaryotic cells

1 October 2017

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Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Redundant control of rereplication in fission yeast

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Cell cycle-dependent proteolysis and phosphorylation of human Mcm10

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

RING finger proteins: mediators of ubiquitin ligase activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

1 October 2017

1 reference

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Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

cDNA cloning, tissue expression, and chromosomal assignment of a mouse gene, encoding a 127 kDa UV-damaged DNA binding protein which is defective in XPE cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

How the cyclin became a cyclin: regulated proteolysis in the cell cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

p48 Activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Targeting protein ubiquitylation: DDB1 takes its RING off

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424545

PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22570418

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKS366

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22570418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22570418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22570418%20AND%20SRC:MED&resulttype=core&format=json